The Effect of Post-operative Exercise in Gastric Cancer Patients: A Randomized Controlled Trial (RCT) Study

Not Applicable

Completed

• Conditions: Gastric Cancer
• Interventions: Behavioral: exercise

• Registration Number: NCT06260293
• Lead Sponsor: Yonsei University

Brief Summary

Medical advancements are enhancing the survival rates of individuals with gastric cancer. The growing population of gastric cancer survivors underscores the importance of managing treatment-related after-effects and side effects. Diminished physical function in cancer patients, particularly following gastric cancer surgery, is linked to increased mortality. The substantial decline in physical activity post-surgery contributes to a notable reduction in cardiorespiratory fitness and lower extremity muscle strength. Early postoperative exercise has demonstrated positive outcomes in colorectal cancer patients, facilitating early hospital discharge and supporting long-term recovery. However, there is a paucity of research on the efficacy of early postoperative exercise in the context of gastric cancer. Therefore, this study aims to evaluate the impact of early postoperative exercise on physical function following gastric cancer surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-03
• Study First Submitted: 2024-01-24
• Study First Submitted QC: 2024-02-06
• Study First Posted: 2024-02-15
• Primary Completion: 2024-07-25
• Study Completion: 2024-07-25
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-10
• Last Update Posted: 2025-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1. Adult men and women 19 years of age or older
2. Pathologically diagnosed gastric cancer
3. Able to undergo radical resection (R0)
4. Scheduled for minimally invasive surgery (MIS)

Exclusion Criteria

1. Pregnant or lactating women
2. Have received chemotherapy and radiation before surgery
3. Scheduled for open surgery
4. Subjects who do not understand or have not given informed consent
5. If healthcare provider (primary care physician) deems it difficult for you to exercise

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Exercise group	exercise	-

Primary Outcome Measures

Name	Time	Method
Shorts Physical Performance Battery(SPPB)	"1 day before surgery", "POD3", "POD 1month"	SPPB is an objective measurement instrument of balance, lower extremity strength, and functional capacity. instrument of balance, lower extremity strength, and functional capacity. The test includes three different domains (walking, sit-to-stand and balance) to assess functional mobility.

Trial Locations

Locations (1)

Department of Surgery, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of