Effect Aerobic Training on Women With Breast Cancer After Chemotherapy

Phase 1

Completed

• Conditions: Cancer; Exercise; Hemoglobins
• Interventions: Behavioral: Exercise training

• Registration Number: NCT02876627
• Lead Sponsor: University of Isfahan

Brief Summary

Introduction: The purpose of this study was to determine the effect of twelve weeks of aerobic exercise program on erythrocyte levels in women with breast cancer after chemotherapy.

Methods: Thirty women with breast cancer after chemotherapy of Sydalshhda hospital (aged between 47-65 years) volunteered for this study, and then randomly selected an exercise (n = 15) and control (n = 15) groups. Exercise group completed a twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve, while the control group were followed. Blood samples including red blood cell counts (RBC), hematocrit (HCT), hemoglobin (HB), peak oxygen consumption before and after 12 weeks of aerobic exercise were measured. For analysis of data, repeated-measures analysis of variance (ANOVA) was used.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-02
• Primary Completion: 2015-06
• Study Completion: 2016-04
• Status Verified: 2016-08
• Study First Submitted: 2016-08-15
• Study First Submitted QC: 2016-08-18
• Last Update Submitted: 2016-08-18
• Study First Posted: 2016-08-24
• Last Update Posted: 2016-08-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

women with breast cancer , who can do a physical, physiological and psychological test; and did not have exercise limitations due to neuromuscular and/or musculoskeletal disease; did not have any health problems that prevented maximum effort on the treadmill test.

Exclusion Criteria

women under erythropoietin treatments, uncontrolled cardiovascular or pulmonary diseases, uncontrolled arrhythmias, orthopedic conditions that would limit exercise participation, refusal for randomization, or participation in aerobic exercise training within 3 months before beginning the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
breast cancer	Exercise training	Effect of exercise training on breast cancer patient

Primary Outcome Measures

Name	Time	Method
effect of exercise on CBC parameters (measured by ELISA methods)	up to 12 weeks

Secondary Outcome Measures

Name	Time	Method
effect of exercise on peak oxygen consumption, measured by vo2 max test	up to 12 weeks