The Effect of 12 Weeks of Aerobic Training Program on Erythrocyte Levels in Women With Breast Cancer After Chemotherapy
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Cancer
- Sponsor
- University of Isfahan
- Enrollment
- 30
- Primary Endpoint
- effect of exercise on CBC parameters (measured by ELISA methods)
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Introduction: The purpose of this study was to determine the effect of twelve weeks of aerobic exercise program on erythrocyte levels in women with breast cancer after chemotherapy.
Methods: Thirty women with breast cancer after chemotherapy of Sydalshhda hospital (aged between 47-65 years) volunteered for this study, and then randomly selected an exercise (n = 15) and control (n = 15) groups. Exercise group completed a twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve, while the control group were followed. Blood samples including red blood cell counts (RBC), hematocrit (HCT), hemoglobin (HB), peak oxygen consumption before and after 12 weeks of aerobic exercise were measured. For analysis of data, repeated-measures analysis of variance (ANOVA) was used.
Investigators
Prof.Mehdi Kargarfard
Principal Investigator
University of Isfahan
Eligibility Criteria
Inclusion Criteria
- •women with breast cancer , who can do a physical, physiological and psychological test; and did not have exercise limitations due to neuromuscular and/or musculoskeletal disease; did not have any health problems that prevented maximum effort on the treadmill test.
Exclusion Criteria
- •women under erythropoietin treatments, uncontrolled cardiovascular or pulmonary diseases, uncontrolled arrhythmias, orthopedic conditions that would limit exercise participation, refusal for randomization, or participation in aerobic exercise training within 3 months before beginning the study.
Outcomes
Primary Outcomes
effect of exercise on CBC parameters (measured by ELISA methods)
Time Frame: up to 12 weeks
Secondary Outcomes
- effect of exercise on peak oxygen consumption, measured by vo2 max test(up to 12 weeks)