KCT0000804已完成未知
Development of antiplatelet therapy protocol for coil embolization of intracranial aneurysm
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 290
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 20(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •Standard vs modified antiplatelet preparation
- •1. Patients with intracranial aneurysm who plan to undergo coil embolization
- •2. Patient aged 20 years and more at the day of enrollment
- •3. Patient with less than 2 of modified Rankin scale score at the day of enrollment
- •4. Patient who agrees and writes out a consent form
- •Short vs long-term dual antiplatelet therapy
- •1. Patients with unruptured aneurysm treated with stent-assisted coiling within 30 days at the day of enrollment
- •2. Patient aged 20 years or more at the day of enrollment
- •3. Patient who agrees and writes out a consent form
排除标准
- •Standard vs modified antiplatelet preparation
- •1. Patient with histoy of hypersensitivity of aspirin, clopidogrel, cilostazol, or prasugrel
- •2. Patient with high possibility of active bleeding such as symptomatic intrcranial hemorrhage or active gastric ulcer
- •3. Patient with bleeding tendency or coagulopathy
- •4. Patient with thrombocytopenia (< 100,000/mm3 of platelet count within three months before enrollment)
- •5. Patient with liver disease (> 100 of AST or ALT within three months before enrollment)
- •6. Patient with renal disease (> 2mg/dL of serum creatinin within three months before enrollment)
- •7. Patient using anticoagulants
- •8. Patients with congestive heart failure or angina unable to be controlled
- •9. Patients with malignant tumor requiring treatment
- •10. Pregnant or breast-feeding woman
- •11. Patient in whom physician decision is disqualificiation
- •Short vs long-term dual antiplatelet therapy
- •1. Patient with modified Rankin scale score of = 1
- •2. Patient with any procedural events
- •3. Patient who received stent-assisted coiling for fusiform or dissected aneurysm
- •4. Patient with side effects of aspirin or clopidogrel
- •5. Patient with underlying disease requiring continuous dual antiplatelet therapy over 12 months
- •6. Patient using anticoagulants
- •7. Patient with a high risk of stroke including arterial fibrillation, occlusion or stenosis of = 30% in extra- or intracranial artery, moyamoya disease, or arteriovenous malformation
- •8. Patient with a high possibility of active bleeding such as symptomatic intracranial hemorrhage or active gastric ulcer
- •9. Patient with bleeding tendency or coagulopathy
- •10. Patient with thrombocytopenia (< 100,000/mm3 of platelet count within three months before enrollment)
- •11. Patient with liver disease (> 100 of AST or ALT within 3 months before enrollment)
- •12. Patient with renal disease (> 2mg/dL of serum creatinine within 3 months before enrollment)
- •13. Patients with congestive heart failure or angina unable to be controlled
- •14. Patients in whom regular follow-up is unable
- •15. Patients with poor medical condition or life expectancy of less than 2 years
- •16. Pregnant or breast-feeding woman
- •17. Patient in whom physician decision is disqualification
研究者
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