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Incidence and extent of a systemic inflammatory response in patients after successful cardiopulmonary resuscitatio

Recruiting
Conditions
I46.0
Cardiac arrest with successful resuscitation
Registration Number
DRKS00009684
Lead Sponsor
niversitätsklinikum Freiburg / Universitäts-Herzzentrum Freiburg - Bad Krozingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

Cardiac arrest with successful resuscitation; Coronary artery disease without acute myocardial infarction

Exclusion Criteria

Preexisting acute- or chronic-inflammatory diseases; Preexisting acute- or chronic-infectious diseases; Multiple organ dysfunction syndrome; Immunosuppressive medication

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quantitative analysis of peripheral blood leucocyte subclasses; Expression of markers of antigen presentation; Leucocyte response to activation by stimulatory agents; Leucocyte and whole blood expression of markers of innate immunity inflammatory signaling, including toll-like receptor and inflammasome signaling; Single blood sample from control group; Sequential blood sampling in patients in the first hours after survived cardiac arrest as well as 1 day and 2 days after resuscitation;
Secondary Outcome Measures
NameTimeMethod
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