Uterine Rupture International Data Acquisition
- Conditions
- Uterine Rupture Gravid
- Registration Number
- NCT03576950
- Lead Sponsor
- Università degli Studi dell'Insubria
- Brief Summary
Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality. Indeed, uterine rupture may cause catastrophic maternal and fetal complications (uterine hemorrhage, hysterectomy with consequent fertility loss, maternal and fetal death or cerebral palsy) which are hardly acceptable within the context of a natural event such as birth.
Uterine rupture can occur during pregnancy, early in labor or following a prolonged labor, most frequently near or at term and, rarely, during early to mid-pregnancy. Its prevalence ranges between 0.006% for women without previous cesarean section (CS) in the western countries, to 25% for women with obstructed labor in African countries.
Pregnancy after myomectomy or CS, vaginal delivery after cesarean sections (VBACs) and vaginal delivery after myomectomy are potentially "at risk" of uterine rupture.
Despite uterine rupture is widely considered a life-threatening condition, so far most of published data refer to case reports or very small case series. In this scenario, the "Uterine Rupture International Data Acquisition" study group would like to collect a large number of events, in order to identify the potential risk factors among different populations through a multivariate analysis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 100
- Women with uterine rupture occurred during pregnancy.
- None.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Uterine rupture A retrospective analysis of 10 years. Women with uterine rupture occurred during pregnancy.
- Secondary Outcome Measures
Name Time Method Gestational age at uterine rupture A retrospective analysis of 10 years. Gestational age, calculated as weeks and days, in which uterine rupture occurred.
Parity A retrospective analysis of 10 years. The number of previous delivery.
Body Mass Index A retrospective analysis of 10 years. The Body Mass Index of each patient in which uterine rupture occurred.
Presence of myomas A retrospective analysis of 10 years. The occurrence of myomas in each patient in which uterine rupture occurred.
Hysterectomy A retrospective analysis of 10 years. The number of cases in which it was necessary to perform hysterectomy after uterine rupture.
Hospital stay A retrospective analysis of 10 years. The hospital stay from the admission to the discharge, expressed in days.
Neonatal complications A retrospective analysis of 10 years. The occurrence of neonatal complications, included neonatal deaths.