Intravenous Immunoglobin Transfusion in Preterm Infants With Encephalopathy of Prematurity
Not Applicable
Recruiting
- Conditions
- Preterm Infants
- Interventions
- Drug: human gamma globulinDrug: non-human gamma globulin
- Registration Number
- NCT02822027
- Lead Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
- Brief Summary
Infection and inflammation is related to increased encephalopathy of prematurities.
- Detailed Description
Animal studies have verified intravenous immunoglobin can reduce brain injury. However, no studies in preterm infants were reported.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- preterm infants with encephalopathy
Exclusion Criteria
- refuse the participate in the trial
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description human gamma globulin human gamma globulin human gamma globulin for infants with encephalopathy of prematurities human gamma globulin non-human gamma globulin human gamma globulin for infants with encephalopathy of prematurities non-human gamma globulin human gamma globulin non-human gamma globulin for infants with encephalopathy of prematurities non-human gamma globulin non-human gamma globulin non-human gamma globulin for infants with encephalopathy of prematurities
- Primary Outcome Measures
Name Time Method structural changes of brain injury 100-days MRI/ultrasound will be used to assess the structural severities of brain injury.
functional changes of brain injury 100-days Bayley score will be used to assess the functional severities of brain injury.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Pediatrics,Daping Hospital
🇨🇳Chongqing, Chongqing, China