A randomized controlled trial on the effectiveness and safety of acupuncture in the treatment of gastrointestinal dysfunction after chemotherapy for colorectal cancer
- Conditions
- Colorectal cancer
- Registration Number
- ITMCTR2100005275
- Lead Sponsor
- Chengdu University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion criteria require that the patients (1) males or females are between 18 and 75 years of age; (2) colonoscopy and histopathological biopsy diagnosed as primary colon cancer or primary high rectal cancer, staging I-III; (3) symptoms related to gastrointestinal dysfunction occurred after chemotherapy, including nausea, vomiting, abdominal distension, diarrhea, constipation, etc.; any item in the gastrointestinal symptom grading scale was scored above 2 points; (4) no abdominal surgery history or more than 3 months after abdominal surgery; (5) The Karnofsky score = 60 points, or the ECOG physical fitness score = 1 point, and the expected survival time is = 3 months; (6) have not received acupuncture treatment and have not participated in other clinical studies within the past 3 months; (7) at least one cycle of chemotherapy has been completed; (8) gastrointestinal dysfunction caused by non-opioids or metabolic imbalances.
Participants who meet one of the following criteria will be excluded: (1) have undergone total colorectal resection or who have a fistula; (2) with severe heart disease, cerebrovascular disease; (3) use warfarin, heparin, etc., or who have abnormal hematopoietic function; (4) unconsciousness, unable to express subjective symptoms and mental illness; (5) long-term use of laxatives, or taking drugs that affect gastrointestinal function and those who are bedridden for a long time.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastrointestinal symptom rating scale;
- Secondary Outcome Measures
Name Time Method SAS;SDS;FACT-C(V 4.0);