NCT00418366已完成1 期
An Open- Label, 2 Part Study to Investigate the Pharmacokinetics, Safety, and Tolerability of MK0431(Sitagliptin Phosphate) in Patients With Varying Degrees of Renal Insufficiency
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 24
- 主要终点
- Determination of the pharmacokinetics of MK0431 (sitagliptin phosphate) in patients with renal insufficiency compared to healthy volunteers
研究概览
简要总结
A study to evaluate the effect of kidney disease, from mild to severe disease, on a diabetes medication
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Determination of the pharmacokinetics of MK0431 (sitagliptin phosphate) in patients with renal insufficiency compared to healthy volunteers
次要结局
- Safety and tolerability in patients with renal insufficiency
研究者
相似试验
已完成
1 期
Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.Pharmacokinetics of IsavuconazoleHealthy VolunteersRenal ImpairedNCT01555866Astellas Pharma Global Development, Inc.49
已完成
1 期
Single Dose, Single Administration Study of Technosphere Inhalation Powder in Diabetic Subjects With Mild or Moderate Kidney Disease Compared to Diabetic Subjects With Normal Kidney FunctionMild NephropathyModerate NephropathyDiabetes MellitusNCT00626249Mannkind Corporation36
已完成
2 期
A Study to Test the Effect of Different Doses of BI 685509 on Kidney Function in People With Diabetic Kidney DiseaseDiabetic NephropathiesNCT04750577Boehringer Ingelheim243
已完成
2 期
A Study to Test the Effect of Different Doses of Avenciguat (BI 685509) on Kidney Function in People With Chronic Kidney DiseaseChronic Kidney DiseaseNCT04736628Boehringer Ingelheim261
已完成
1 期
A Study to Learn How the Body Processes the Study Medicine Called PF-07923568 in People With Loss of Kidney FunctionRenal ImpairmentNCT06037031Pfizer16