Diabetic Shoulder Mobility

Not Applicable

Completed

• Conditions: Diabetes Mellitus

• Registration Number: NCT02162212
• Lead Sponsor: Washington University School of Medicine

Brief Summary

The primary goal of this project is to determine how advanced glycation end-product (AGEs) accumulation and shoulder movement (humeral thoracic range of motion and "activity count") interact to contribute to shoulder limited joint mobility (LJM), pain and disability, and if an intervention consisting of a tailored dose of stretching and active shoulder movement can reduce these problems in people with diabetes mellitus (DM). The investigators will focus on the following measures that span health domains; Skin intrinsic fluorescence to measure AGEs; Ultrasound to measure supraspinatus tendon thickness; 3 dimensional joint range of motion and "activity counts" to measure shoulder movements; and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire to measure patient reported pain and disability. The investigators will test the innovative hypothesis that metabolic and movement factors interact to cause severe shoulder problems in people with DM and that an optimized shoulder movement intervention can have an important impact on reducing the development of limited joint mobility, pain and disability in this population.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-06-09
• Study First Submitted QC: 2014-06-10
• Study First Posted: 2014-06-12
• Study Start: 2014-09
• Primary Completion: 2016-10-12
• Study Completion: 2016-10-12
• Status Verified: 2017-11
• Last Update Submitted: 2017-11-03
• Last Update Posted: 2017-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• individuals with type 2 DM and duration of diagnosed diabetes more than 10 years OR type 2 DM and presence of a 'positive prayer sign' OR shoulder flexion < 150 degrees; disability of arm, shoulder and hand (DASH) scores in the range of <70%; between the age of 40-70 will be recruited.

Exclusion Criteria

• currently diagnosed adhesive capsulitis
• diagnosed rotator cuff tear
• recent (6 months) upper extremity injury and/or fractures
• surgery in the upper extremity or thorax
• cervical radiculopathy
• thoracic outlet syndrome
• stroke with residual upper extremity involvement
• severe skin allergies in area to be tested
• rheumatic conditions
• known connective tissue diseases
• carpal tunnel syndrome
• use of a cane
• individuals who engage in heavy upper extremity/ overhead use (ie, painters, tennis players) because they likely have a different mechanism of injury than those with low shoulder activity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Arm elevation.	One year	Arm elevation is a composite of shoulder (glenohumeral) and scapular motion and will be measured using goniometry and computer assisted kinematics. Glenohumeral elevation and external rotation motions are the main focus.

Secondary Outcome Measures

Name	Time	Method
Disability of the Arm, Shoulder, and Hand (DASH) questionnaire	One year	The DASH is an established, standardized measure used to characterize pain and disability in the upper extremity.

Trial Locations

Locations (1)

Washington University School of Medicine; 🇺🇸 Saint Louis, Missouri, United States