Xylitol Clinical Studies for Prevention - Xylitol Dose Study (Gum 1)
Completed
- Conditions
- Oral HealthDental CariesDental caries
- Registration Number
- ISRCTN73818624
- Lead Sponsor
- niversity of Washington (USA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
Adult, male & female, with screening plaque mutans streptococci level greater than 10,000 CFU/ml
Exclusion Criteria
1. Gastro-intestinal diseases/problems
2. Phenylalanine intolerant
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie xylitol's inhibition of Streptococcus mutans biofilm formation in dental caries prevention?
How does xylitol gum compare to fluoride-based therapies in reducing caries incidence in pediatric populations?
Which salivary biomarkers correlate with xylitol efficacy in ISRCTN73818624 oral health trials?
What are the long-term safety profiles of high-dose xylitol consumption in caries prevention studies?
How do xylitol-chlorhexidine combination therapies synergistically target cariogenic bacteria compared to monotherapies?