Assessment of Suspected Intracranial Malignancy Using 3'-Deoxy-3'18 F-flourothymidine PET

Terminated

• Conditions: Brain Tumor
• Interventions: Procedure: FLT-PET scan

• Registration Number: NCT00775320
• Lead Sponsor: University of Oklahoma

Brief Summary

The primary objective of this study is to detect and quantify tumor cells of high grade malignant gliomas and metastatic brain lesions both before and after initial surgical resection in a cohort of newly diagnosed patients.

Detailed Description

In this study, 35 patients will be selected to undergoing sequential imaging with FLT-PET. Prior to surgical resection, patients will undergo a preliminary FLT-PET. Additional FLT scans for a maximum of four scans.

Study Timeline

• Study Start: 2008-10
• Study First Submitted: 2008-10-17
• Study First Submitted QC: 2008-10-17
• Study First Posted: 2008-10-20
• Primary Completion: 2010-08
• Study Completion: 2010-08
• Status Verified: 2019-11
• Last Update Submitted: 2019-11-20
• Last Update Posted: 2019-11-25

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

• 18 years or older
• Women must not be pregnant or breast feeding
• Histologic or strong radiologic suspicion of high grade malignant glioma or ogliometastatic tumor(s)

Exclusion Criteria

• May not have received previous therapy for their malignancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Brain tumor FLT-PET	FLT-PET scan	Those diagnosed with a brain tumor and are to undergo surgery

Trial Locations

Locations (1)

University Of Oklahoma Health Sciences Center; 🇺🇸 Oklahoma City, Oklahoma, United States