Investigation of the effect of hydrogel wound dressing based on polyacrylic acid and xanthan gum in the treatment of burn injury

Phase 3

Recruiting

Conditions: Second degree burn.
Burn of unspecified degree of head, face, and neck
T20.0

Registration Number: IRCT20161001030072N4

Lead Sponsor: Rasht University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 42

Inclusion Criteria

Thermal burns with flame or boiling water
Second degree burns
Burn percent range Between 20-50%
Refer to the treatment center within less than 24 hours after the burn
Normal hemoglobin and total protein levels are normal
Male or female patients in age range 18 to 65 years
Written consent form by the patients
Body mass index between 18-30 kg/m2

Exclusion Criteria

Having background diseases ( anemia, diabetes, cardiovascular diseases, immunodeficiency disorder)
Lactating women Pregnant women

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ocal out comes. Timepoint: At the beginning of the study (before the intervention) and 1, 3, 7, 14 and 28 days after applying the hydrogel wound dressing. Method of measurement: Clinical observations and filling the checklist in 6 time points.;Systemic outcomes. Timepoint: At the beginning of the study (before the intervention) and 1, 3, 7, 14 and 28 days after applying the hydrogel wound dressing. Method of measurement: Clinical observations and filling the checklist in 6 time points.

Secondary Outcome Measures

Name	Time	Method
Infection. Timepoint: At the beginning of the study (before the intervention) and 1, 3, 7,14, and 28 days after applying the hydrogel wound dressing. Method of measurement: Based on examination done by evaluators.;Hospital stay. Timepoint: At discharge. Method of measurement: Based on patients' files.;Total fluid requirement. Timepoint: At discharge. Method of measurement: Based on patients' files.;Graft to TBSA (total body surface area) percent ratio. Timepoint: At the admission. Method of measurement: Measurements based on Wallace criteria.