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Clinical Trials/NCT01083433
NCT01083433
Completed
N/A

Intensive Diabetes Clinic and Intermittent Continuous Glucose Monitoring in Adolescents With Type 1 Diabetes Mellitus in Poor Glycemic Control

University Hospitals Cleveland Medical Center1 site in 1 country68 target enrollmentMay 2010

Overview

Phase
N/A
Intervention
Not specified
Conditions
Type 1 Diabetes Mellitus
Sponsor
University Hospitals Cleveland Medical Center
Enrollment
68
Locations
1
Primary Endpoint
Glycemic Control
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this research study is to find out ways to help pre-teens and teens and their families to improve diabetes control and to help with the burden of diabetes management. Specifically, the study aims to find out if coming to diabetes clinic more frequently and for a longer period of time helps adolescents with diabetes, and if adolescents who wear a continuous glucose monitor (CGM) for 3-5 days a month will have better diabetes control.

Detailed Description

Good glycemic control is critical in preventing chronic complications of type 1 diabetes. However, achieving good glycemic control remains elusive for many adolescents. This study evaluates two clinic-based approaches for improving glycemic control in adolescents with poorly controlled type 1 diabetes - an intensive diabetes support and education program alone and the same intensive diabetes support and education program together with continuous glucose monitoring - in comparison with standard diabetes care.

Registry
clinicaltrials.gov
Start Date
May 2010
End Date
October 2011
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sarah A. MacLeish

Physician

University Hospitals Cleveland Medical Center

Eligibility Criteria

Inclusion Criteria

  • Type 1 diabetes mellitus of at least 12 months duration, followed by Rainbow Babies and Children's Pediatric Endocrinology and Diabetes Division
  • Most recent HbA1c \>= 8.5%
  • Patients must be willing to check their blood sugar at least 4 times daily while wearing the CGM
  • Patients and families must be willing to come to diabetes clinic once a month for 4 months

Exclusion Criteria

  • Inability to understand and/or speak the English language
  • Pregnancy
  • Psychological counseling with Dr. Rebecca Hazen regarding diabetes adherence prior to the study

Outcomes

Primary Outcomes

Glycemic Control

Time Frame: Baseline and visit 4

Serum hemoglobin A1c (HbA1c) will be measured in all groups at the baseline visit and visit 4.

Secondary Outcomes

  • Number of Hypoglycemic Excursions (CGM Glucose <70 mg/dL)(Total from baseline to visit 4)
  • Satisfaction With Intensive Diabetes Clinic and Usage of the Continuous Glucose Monitor(Visit 4)
  • Adherence to Prescribed Diabetes Regimen(Baseline and visit 4)
  • Diabetes Knowledge(Baseline and month 4)
  • Insulin Dose Changes(Baseline and visit 4)

Study Sites (1)

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