CBCT Analysis of the Craniofacial Architecture in Young, Non-overweight Apneic Adult Phenotype
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- maxillary volume
研究概览
简要总结
This prospective, controlled study will compare the 3D cephalometric analysis of bone and craniofacial soft tissues in young (18-35 years) non-overweight apneic adults phenotype between a test group (with AHI 15) and a control group (healthy subjects with AHI < 15).
详细描述
Objectives The goal of this study is to determine an accurate bone and soft tissue phenotype for the non-overweight apneic young adult.
Materials and Methods This study was approved by the ethics medical committee of the University hospital of Liege.
This prospective, controlled study will compare cephalometric 3D analysis of bone and craniofacial soft tissue phenotype of young, non-overweight apneic adults using cephalometric 3D analysis between a test group (with AHI 15) and a control group (healthy subjects with AHI < 15).
The inclusion criteria were : (1) patients aged between 18 and 35 years ; (2) Body Mass Index (BMI) lower than 30kg/m² ; (3) alcohol consumption less than 4 unit per day ; (4) tabacco use less than 6 cigarettes per day ; (5) no illicit drug use ; and (6) absence of chronic pathology or medication.
The exclusion criteria were : (1) presence of an acute illness on the day of admission ; (2) patients treated with orthognathic surgery after apnea screening ; (3) patients with polysomnography with a sleep treatment device (PPCN or Mandibular advancement device).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •(1) patients aged between 18 and 35 years ;
- •(2) Body Mass Index (BMI) lower than 30kg/m² ;
- •(3) alcohol consumption less than 4 unit per day ;
- •(4) tabacco use less than 6 cigarettes per day ;
- •(5) no illicit drug use ; and
- •(6) absence of chronic pathology or medication.
排除标准
- •(1) presence of an acute illness on the day of admission ;
- •(2) patients treated with orthognathic surgery after apnea screening ;
- •(3) patients with polysomnography with a sleep treatment device (PPCN or Mandibular advancement device).
结局指标
主要结局
maxillary volume
时间窗: 2month
maxillary volume with 3D cephalométric analysis
次要结局
未报告次要终点
研究者
Jadoul Mathilde
post graduated dento facial orthopedic department
Centre Hospitalier Universitaire de Liege