DRKS00006849Active, not recruiting未知
Therapeutic Response and Neurobiological Prediction Markers in Auditory Verbal Hallucinations
Translational Research Center, Division of Systems Neuroscience of Psychopathology, University Hospital of Psychiatry0 sites12 target enrollmentStarted: November 6, 2014Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 12
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Non-randomized controlled study
- Masking
- Blinded (masking used)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (—)
- Sex
- All
Inclusion Criteria
- •ICD-10: patients of the University Hospital of Psychiatry in Bern with schizophrenia (F20), acute and transient psychotic disorder (F23), or schizoaffective disorder (F25), prone to AVH in the acute phases of the disorder
- •Patients not declining conventional antipsychotic treatment (Treatment arms A, F, G) or patients declining conventional antipsychotic treatment (Treatment arm B-E)
- •Right-handedness
- •Able to give informed written consent to participate in the study and ability to follow the procedures of the study (no language problems, psychological disorders, dementia, etc.)
Exclusion Criteria
- •Involuntary commitment (individuals with symptoms of severe mental illness endangering themselves or others are committed into treatment in a hospital)
- •Other psychiatric or neurological disorder than F20 or F25
- •Skin disease on the head
- •Participation in other clinical studies
- •Non-removable metallic components (splinters, cardiac pacemakers, metal clips, metal implants, cochlear-implants, insulin pumps, etc.)
- •Tattoos on or near the head
- •Permanent make-up
- •Claustrophobia
- •Signs of increased cerebral excitability (EEG)
- •For female patients:
- •Pregnancy or breast feeding
- •Intention to become pregnant during the course of the study
- •Lack of safe contraception, defined as: Female participants of childbearing potential, not using and not willing to continue using a medically reliable method of contraception for the entire study duration, such as oral, injectable, or implantable contraceptives, or intrauterine contraceptive devices, or who are not using any other method considered sufficiently reliable by the investigator in individual cases
Investigators
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