Effect of Bright Light Treatment On Elders In A Long Term Care Environment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- assessment of cognitive functioning using MicroCog
研究概览
简要总结
The investigators hypothesize that significant exposure to artificial morning bright light (approximately 200 lux of primarily blue light at eye level for thirty minutes daily) as compared to sham bright red light (placebo) will:
- improve sleep quality
- improve cognitive scores
- improve depression scores
- improve quality of life scores.
详细描述
Bright light therapy has been shown to improve depression and insomnia in multiple studies. These are common conditions among elders, particularly those residing in long term care environments. Bright light therapy has been inadequately studied in the geriatric population. We will show that a groups of twenty elders can simultaneous be exposed to bright light and that it will result in improvements in multiple realms of behavior and quality of life. Elders will be tested with a number of neuropsychological test batteries prior to exposure to bright light and again at the end of a four week exposure. Some subjects will have daytime and night time activity levels monitored with actigraphy. Cortisol and melatonin levels will be obtained prior to and at the end of the exposure period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •residents in Masonic Villages, Elizabethtown, PA long term care
- •ability to give informed consent and complete the neuropsychological tests
排除标准
- •blindness
- •severe illness expected to preclude the ability to complete treatment
- •moderate to severe dementia that precludes the ability to complete testing
- •light sensitivity making treatment to light therapy uncomfortable
研究组 & 干预措施
bright light
Bright light has been shown to entrain circadian rhythm so our treatment arm will use thirty minutes of early morning exposure to bright blue light for a four week period.
干预措施: exposure to bright light (Other)
red light
Low level red light is a weak entrainment stimulus of circadian rhythm. Elders in the control group will be exposed to low level red light as a placebo for thirty minutes daily for four weeks.
干预措施: low luminosity red light (Other)
结局指标
主要结局
assessment of cognitive functioning using MicroCog
时间窗: once prior to intervention, once near the end of intervention, once four weeks after intervention
Assessment of mood using the Geriatric Depression Scale
时间窗: once prior to intervention, once near the end of intervention, once four weeks after intervention
assessment of quality of life using the SF-36
时间窗: once prior to intervention, once near the end of intervention, once four weeks after intervention
assessment of sleep quality using the Pittsburgh Sleep Quality Index
时间窗: once prior to intervention, once near the end of intervention, once four weeks after intervention
assessment of mood using the Profile of Moods Survey
时间窗: weekly throughout the duration of the study
assessment of sleep quality using the Epworth Sleepiness Scale
时间窗: weekly throughout the duration of the study
day and nightime activity level (5 subjects per group only) using Actigraphy
时间窗: two weeks prior to light exposure and the second two weeks during light exposure (continuous measurements)
次要结局
- salivary melatonin levels(once prior and near the end of light exposure period)
- salivary cortisol levels(once prior and near the end of light exposure period)