Related Factors of Hp Infection in Physical Examination and Community Population in Hunan Province: A Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,516
- 试验地点
- 1
- 主要终点
- Helicobacter pylori eradication rate
研究概览
简要总结
This study intends to investigate the prevalence and risk factors of Helicobacter pylori (H. pylori) infection in the population of physical examination centers and communities. The physical examination population from the health management center of the Third Xiangya Hospital and the family-based community residents in Changsha were randomly selected. The H. pylori infection was detected by carbon-13 urea breath test (13C-UBT), and the related factors of H. pylori infection were investigated by questionnaire survey. The study provides supporting evidences to implement family-base H. pylori management to curb its intrafamilial spread. The results have important clinical implications in refinement of eradication strategies and impact on public health policy formulation for related disease prevention.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 4 Years 至 90 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •population aged 4-90 years, no requirement for gender;
- •the physical examination population from the health management center of the Third Xiangya Hospital;
- •the family-based community residents in Changsha City [families containing two or more family members (living together for more than 10 consecutive months per year) and the family members aged 3 years and above];
排除标准
- •people with use of antibiotics, bismuth or Chinese traditional medicines with antibacterial effects in the previous 4 weeks of 13C-UBT, or H2 receptor antagonists, PPIs, P-CAB or other drugs affecting H. pylori activity within the previous 2 weeks of 13C-UBT;
- •people with H. pylori treatment within the past 3 months;
- •People who fasted less than 3 hours before 13C-UBT;
- •people with other contraindications to performing 13C-UBT;
- •people living alone in a family;
- •people with incomplete questionnaire information;
- •people with serious diseases or clinical conditions that may interfere with the evaluation of the results of the study, such as severe heart, liver, lung, and renal insufficiency, low immunity, and so on;
- •people with mental illness and communication disorders;
- •people deemed unsuitable by the researchers to participate in this project;
结局指标
主要结局
Helicobacter pylori eradication rate
时间窗: through study completion, an average of 1 week
carbon-13 urea breath test
次要结局
未报告次要终点
研究者
Fen Wang
Professor
The Third Xiangya Hospital of Central South University