Tyvaso Dosing and Titration Evaluation: TyTRATE Registry
- Conditions
- Pulmonary Arterial Hypertension
- Registration Number
- NCT01799473
- Lead Sponsor
- United Therapeutics
- Brief Summary
This prospective, observational, multi-center, patient registry will follow patients who are newly initiated on Tyvaso for the treatment of Pulmonary Arterial Hypertension (PAH). Once enrolled, the patients' dose and titration will be followed for the first 6 months of treatment with Tyvaso.
A call-center will contact the patients directly at weeks 1, 2, 3, 4, 8, 12, 16, 20, and 24 to review their dose and titration schedule. In addition to patient-reported dosing data, some patient demographic information, will be collected by the investigative site at Baseline.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 98
- Are newly prescribed Tyvaso for the treatment of PAH and plan to initiate therapy
- Are willing and able to be contacted by the patient call center.
- Have previously received Tyvaso.
- Are currently enrolled in an interventional (non-FDA approved) PH clinical trial.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Observe dose changes of Tyvaso over time 6 Months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (50)
UCLA Medical Center
🇺🇸Los Angeles, California, United States
The Regents of the University of California
🇺🇸La Jolla, California, United States
Southern California Permanente
🇺🇸Pasadena, California, United States
Central Coast Chest Consultants
🇺🇸San Luis Obispo, California, United States
Pacific Sleep Disorders Center
🇺🇸Stockton, California, United States
Prime Healthcare, PC
🇺🇸West Hartford, Connecticut, United States
Bay Area Cardiology Associates, PA
🇺🇸Brandon, Florida, United States
Florida Lung & Sleep Specialist
🇺🇸Celebration, Florida, United States
On Site Clinical Solutions
🇺🇸Cumming, Georgia, United States
Sacred Heart Medical Group
🇺🇸Pensacola, Florida, United States
Cardiology Consultants
🇺🇸Pensacola, Florida, United States
Pensacola Lung Group
🇺🇸Pensacola, Florida, United States
Doctors Hospital of Augusta
🇺🇸Augusta, Georgia, United States
Duluth Biomedical Research
🇺🇸Duluth, Georgia, United States
Gwinnett Consultants in Cardiology
🇺🇸Lawrenceville, Georgia, United States
Atlanta Cardiology Consultants
🇺🇸Roswell, Georgia, United States
Dor Heart and Vascular Clinic
🇺🇸Gurnee, Illinois, United States
Queens Medical Center - Honolulu
🇺🇸Aiea, Hawaii, United States
Advocate Medical Group
🇺🇸Oakbrook, Illinois, United States
Loyola University of Chicago
🇺🇸Maywood, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸Peoria, Illinois, United States
Pulmonary and Care Associates of Baltimore
🇺🇸Pikesville, Maryland, United States
MedStar Health Institute
🇺🇸Hyattsville, Maryland, United States
Presbyterian Heart Group
🇺🇸Albuquerque, New Mexico, United States
Madison Medical Affiliates
🇺🇸Milwaukee, Michigan, United States
Singing River Health System
🇺🇸Pascagoula, Mississippi, United States
AZ Perfection Clinical
🇺🇸Union, New Jersey, United States
New York Methodist Hospital
🇺🇸Brooklyn, New York, United States
Asheville Cardiology Associates
🇺🇸Asheville, North Carolina, United States
Sanford Heart Hospital
🇺🇸Fargo, North Dakota, United States
Southwest General Health Center
🇺🇸Middleburg Heights, Ohio, United States
Midwest Pulmonary & Sleep Research
🇺🇸Dayton, Ohio, United States
WellSpan Health
🇺🇸York, Pennsylvania, United States
The Lankenau Institute for Medical Research
🇺🇸Wynnewood, Pennsylvania, United States
Maury Regional Medical Center
🇺🇸Columbia, Tennessee, United States
The Rector and Visitors of the University of Virginia
🇺🇸Charlottesville, Virginia, United States
Carilion Medical Center
🇺🇸Roanoke, Virginia, United States
Pulmonary & Sleep Research
🇺🇸Spokane, Washington, United States
CardioPulmonary Research Center
🇵🇷Guaynabo, Puerto Rico
The Cleveland Clinic Foundation
🇺🇸Cleveland, Ohio, United States
Pediatrix Cardiology Associates
🇺🇸Tampa, Florida, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
🇺🇸Chicago, Illinois, United States
Children's Hospital Medical Center
🇺🇸Cincinnati, Ohio, United States
Pulmonary Consultants of San Antonio, PA
🇺🇸San Antonio, Texas, United States
The Medical College of Wisconsin, Inc.
🇺🇸Milwaukee, Wisconsin, United States
Clarian Health Methodist Hospital
🇺🇸Indianapolis, Indiana, United States
INTEGRIS Baptist Medical Center, Inc
🇺🇸Oklahoma City, Oklahoma, United States
Medical College of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States
Heart and Lung Associates, PC
🇺🇸Bayside, New York, United States
University of Wisconsin School of Medicine and Public Health
🇺🇸Madison, Wisconsin, United States