跳至主要内容
临床试验/CTRI/2026/01/102263
CTRI/2026/01/102263
尚未招募
2/3 期

Clinical evaluation of treatment on class I and II gingival recession with subepithelial connective tissue graft with and without low-level laser therapy- a split-mouth clinical study.

Pooja Hungund1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2026年2月16日最近更新:

概览

阶段
2/3 期
状态
尚未招募
发起方
Pooja Hungund
入组人数
10
试验地点
1
主要终点
Clinical parameters such as gingival index and plaque index (as described by Loe and Silness), recession depth (RD), probing depth (PD), clinical attachment level (CAL), and width of keratinized tissue (WKT) will be measured.

概览

简要总结

Gingival recession (GR) is described as an apical displacement of the gingival margin in relation to the cementoenamel junction, exposing the root surface to the oral cavity environment. The main indication to treat gingival recessions is to increase soft tissues thickness and stability to facilitate plaque control and prevent further periodontal inflammation and break-down or root caries.

Coronally advanced flap (CAF), although a gold standard, is technique sensitive, and has limitations. A novel minimally invasive surgical approach The Pouch and  Tunnel  technique has been recently introduced for the management of isolated gingival recession and ensures mobilization of flap for graft coverage.

Low-level laser therapy (LLLT) was first described in the literature by Mester et al. as a therapeutic method in several areas of medicine and dentistry. Recently, LLLT has also been used in the treatment of gingival recession. However, the basic mechanism by which LLLT may affect periodontal wound healing still remains unclear due to the lack of evidence.

To our knowledge, studies evaluating LLLT associated with root coverage procedures using Pouch and Tunnel technique and subepithelial connective tissue graft are rare. Therefore, the aim of this study is to evaluate the clinical results of bilateral root coverage of GR associated with Subepithelial Connective Tissue Graft (SCTG) alone or combined with low-level laser therapy (SCTG + LLLT).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
20.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Patients who agreed to participate in the study by signing the written informed consent.
  • Patients with an age between 20 and 45 years
  • Presence of bilateral multiple adjacent maxillary facial gingival recessions (2–3 mm) based on Cairo et al classification as RT1 and Miller’s Class I and II in the anterior or premolars.
  • Presence of identifiable cementoenamel junction (CEJ)
  • Patients with full mouth visible plaque score and Bleeding score of less than or equal o 20%.

排除标准

  • Patients with a history of any systemic illness which hinder the healing of the surgical site.
  • Patients using medications that will interfere with the healing process or that contraindicate the surgical procedure.
  • Patients who received any surgical treatment during the previous 24 months on the selected sites.
  • Pregnant or lactating women.
  • Patients with smoking habit.

结局指标

主要结局

Clinical parameters such as gingival index and plaque index (as described by Loe and Silness), recession depth (RD), probing depth (PD), clinical attachment level (CAL), and width of keratinized tissue (WKT) will be measured.

时间窗: Baseline and 3 months

次要结局

未报告次要终点

研究者

发起方
Pooja Hungund
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Pooja Hungund

The Oxford Dental College

研究点 (1)

Loading locations...

相似试验