Incidence of Fat Embolism With Computer Assisted Total Knee Arthroplasty

Completed

• Conditions: Fat Embolism Syndrome

• Registration Number: NCT00656877
• Lead Sponsor: Marshall University

Brief Summary

The study to determine the if the incidence of Fat Embolism is decreased using Computer Assisted technology when performing a Total Knee Arthroplasty.

Detailed Description

Computer assisted total knee arthroplasty is at its inception currently. There are many unknowns about this specific technique, particularly when it comes down to fat embolism syndrome. There is a high incidence of fat embolism during total knee arthroplasty as seen both by echocariography as well as sampling of right atrial blood. During a jig-based, or traditional, total knee arthroplasty, a rod is placed inside the femur, and sometimes the tibia as well. Intrusumentations of the medullary canal is known to cause fat embolism. Fat embolism is a syndrome which can produce post-operative confusion, hypoxemia, all the way to post-op and intra-operative death.

Computer assisted total knee arthroplasty does not use intramedullary jigs. It is presumed that by not instrumenting the medullary canal, the rate of fat embolism will be significantly reduced.

Fifty patient s will be studied while they are having a computer assisted total knee arthoplasty. A PICC line will be placed in their arm by an interventional radiologist pre-operatively. This PICC line will be thread into the right atrium. Right atrial blood will be sent to pathology every 10 minutes during the 60 to 90 minute procedure and at intervals post-op. The right atrial blood will be stained for bone marrow elements.

This study is to presumed to show yet another benefit of computer assisted surgery.

Study Timeline

• Study Start: 2006-01
• Study First Submitted: 2007-12-27
• Primary Completion: 2008-03
• Study Completion: 2008-03
• Status Verified: 2008-04
• Study First Submitted QC: 2008-04-04
• Last Update Submitted: 2008-04-04
• Study First Posted: 2008-04-11
• Last Update Posted: 2008-04-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Must be a candidate for Computer Assisted Total Knee Arthroplasty

Exclusion Criteria

• Mentally incompetent patients excluded

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Marshall University School Of Medicine, Department of Orthopaedics; 🇺🇸 Huntington, West Virginia, United States