Clinical evaluation for primary complex points on improving the effect of obstinate insomnia and its influence on changes of brain transmitters
Phase 1
- Conditions
- Persistent insomnia
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Insomnia patients who meet the criteria of TCM diagnosis and western medicine diagnosis;
2. between 18 and 65 years of age (including 18 and 65 years of age);
3. No insomnia related treatment was received 1 week before treatment;
4. Voluntary participation in this trial, strictly abide by the treatment prescribed in this study, obey the doctor arrangement, and can adhere to the treatment and follow-up. sign informed consent.
Exclusion Criteria
1. Anemia or diabetes, and women who are breastfeeding or during pregnancy;
2. Patients with organic diseases or mental illness.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 5-HT;GABA; Insomnia Severity Index;TCM Symptom Scale;NE;MLT;5-HIAA;Sleep rate;IL-6;DA;Pinsburgh Sleep Quality Index;IL-1;TNF;
- Secondary Outcome Measures
Name Time Method Hamilton Anxiety Scale; Epworth somnolence scale; Hamilton Depression Scale;