NL-OMON47772
Completed
Not Applicable
Evaluating retinal blood flow autoregulation by means of Optical Coherence Tomography Angiography (OCT-A)<br> - Autoregulation of retinal blood flow<br>
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 125
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •subjects between 50 and 65 years;\- Group \#1: Symptomatic low blood pressure individuals
- •Defined as having at least one of: systolic blood pressure below 98 mmHg or diastolic blood pressure below 58 mmHg (without the use of any antihypertensive treatment), and at least one of:
- •a) migraine:
- •Migraine is defined as already diagnosed, or a score of 4 or 5 in the corresponding section of the questionnaire, according to the Migraine Screening Questionnaire.
- •b) orthostatic hypotension:
- •Orthostatic hypotension is defined as already diagnosed, or a sustained reduction of systolic blood pressure (SBP) of at least 20 mmHg or diastolic blood pressure (DBP) of 10 mmHg within 3 minutes of standing.
- •c) cold intolerance:
- •Cold intolerance is defined as a score of 30 or more in the corresponding section of the questionnaire.;\- Group \#2: Asymptomatic low blood pressure individuals
- •Defined as having at least one of: systolic blood pressure below 98 mmHg or diastolic blood pressure below 58 mmHg (without the use of any antihypertensive treatment), and none of the symptoms described in Group \#1\.;\- Group \#3: Asymptomatic normal blood pressure individuals
- •Defined as having systolic blood pressure between 113 and 143 mmHg, and diastolic blood pressure between 67 and 85 mmHg (without the use of any antihypertensive treatment), and none of the symptoms described in Group \#1\.;\- Group \#4: Asymptomatic untreated high blood pressure individuals
Exclusion Criteria
- •visual acuity less than 0\.8
- •intra\-ocular pressure more than 21 mmHg
- •any visual field defect
- •sphere of more than (\+/\-)3D or cylinder of more than (\+/\-)2D
- •positive family history (father, mother, brother or sister) of glaucoma
- •OCT\-A image quality of 6 or less
- •pathological fundus photographs
- •diagnosed diabetes mellitus of any type
- •medical history of cerebrovascular disease, heart disease or severe anemia
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Autoregulation of retinal blood flowNL-OMON26189niversity Medical Center Groningen125
Recruiting
Phase 4
Retinal Blood Flow and AutoregulationGlaucomaNCT05344274University of Maryland, Baltimore90
Completed
Not Applicable
Regulation of Retinal Bloodflow PressureRetinal BloodflowNCT03398616Gerhard Garhofer17
Completed
Not Applicable
Assessing cerebral blood flow in hypertensive pregnant women by performing eye usgCTRI/2017/05/008689PGIMER180
Completed
Not Applicable
Choroidal Blood Flow Regulation During Isometric Exercise: Effects of Ca2+-Channel BlockadeOcular PhysiologyRegional Blood FlowNCT00280462Medical University of Vienna21