KCT0007807尚未招募未知
Effectiveness of Cilostazol on Cognitive Decline in High-risk Elderly PeOple with Ischemic Stroke Compared to Aspirin or ClopidogrEl
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 2,362
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 65(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •1. History of ischemic stroke (more than 3 months ago)
- •2. At high risk of dementia
- •(1) Aged 75 years and older,
- •(2) Aged 65-74 years and meeting one of the following conditions:
- •(i) diabetes mellitus
- •(ii) severe WMH (Fazekas grade III)
- •(iii) medial temporal atrophy (Scheltens’ visual grade III or more)
- •(iv) multiple cerebral microbleeds (=5)
- •(v) multiple lacunes (>5)
- •(vi) APOE e4 allele (+)
- •3. patients signed informed consent
排除标准
- •1. Subjects who are illiterate or have neurological deficits to a degree that would interfere with cognitive tests including hearing difficulty, poor cooperation, or severe aphasia.
- •2. Subjects who have severe disability (e.g., modified Rankin scale > 3)
- •3. Subjects who have dementia or major psychiatric illness (e.g., schizophrenia, bipolar disorder, major depression) at the time of randomization
- •4. Subjects who have compelling indication for anticoagulation or dual antiplatelet therapy
- •5. Subjects who have medical conditions that make it impossible to follow them up for 5 years (e.g., malignancies with life expectance less than 5 years)
研究者
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