on invasive imaging of [18F]HX4 with Positron-Emission-Tomography (PET) in Head and Neck Cancer.
- Conditions
- Cancer of the Head and NeckSquamous cell carcinomas of head and neck10027655
- Registration Number
- NL-OMON39184
- Lead Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
- Histological or cytological confirmed HNSSC of the oral cavity, oropharynx, hypopharynx, larynx, T2-T3-T4, any N, M0;- Tumor (or lymph node) diameter * 2,5 cm;- WHO performance status 0 to 2;- Scheduled for primary curative (concurrent chemo-) radiotherapy;- No previous surgery to the head and neck;- No previous radiation to the head and neck;- Adequate renal function (calculated creatinine clearance at least 60 ml/min) ;- The patient is willing and capable to comply with study procedures;- 18 years or older;- Have given written informed consent before patien registration
No recent (< 3 months) myocardial infarction;- No Uncontrolled infectious disease;- Not pregnant or breast feeding and willing to take adequate contraceptive measures during the study
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Visualisation of tumor hypoxia with [18F] HX4 PET imaging</p><br>
- Secondary Outcome Measures
Name Time Method