A phase I/II study of preoperative chemoradiotherapy with S-1, Celecoxib and Radiation for locally advanced rectal cancer - chemoradiotherapy with S-1, Celecoxib and Radiation for locally advanced rectal cancer

Department of frontier surgery Graduate school of medicine, Chiba University0 个研究点目标入组 20 人开始时间: 2014年1月10日最近更新: 2023年10月17日

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•1). Even if is an overlap cancer case of the activity or heterochrony; a treatment-free and disease-free period the case (but cancer in the epithelium and the skin cancer are excluded) less than five years 2). It is a case with a history of the radiation therapy including the irradiation after art for a lesion 3). with the diarrhea (water-like flight) 4). receiving flucytosine 5). It is a case with the past of hypersensitivity for S-1, an ingredient of celecoxib 6). The case (diabetes having poor heart, kidney, liver failure, control) with serious complications 7). Aspirin asthma or a case with the past 8). with peptic ulcer of the activity 9). uses an NSAID regularly 10). hydrothorax, abdominal dropsy to need urgent treatment 11). having an infectious disease of the activity few for tumor in itself 12). having the intestinal tract paralysis, ileus 13). with the possibility (intention) of the pregnancy, a pregnant woman or a nursing girl, a case without the intention to prevent conception 14). A perioperative patient of the coronary bypass rebuilding art 15). In addition, the case that I judged to be inappropriate though the examination medical attendant carried out the final examination safely

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Department of frontier surgery Graduate school of medicine, Chiba University