NCT06037941
Recruiting
Not Applicable
Breathprinting (E-Nose) Technology to Measure Response to Treatment of Malignant Pleural Mesothelioma (MPM) Through MPM-Specific Volatile Organic Compounds Detected in Exhalates
ConditionsMalignant Pleural Mesothelioma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Malignant Pleural Mesothelioma
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Enrollment
- 20
- Locations
- 7
- Primary Endpoint
- Change of MPMspecific VOCs
- Status
- Recruiting
- Last Updated
- 7 months ago
Overview
Brief Summary
The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard treatment for malignant pleural mesothelioma (MPM). The researchers will study how E-Nose breathprints change over time as people receive standard treatment for MPM. They will also look at how changes in people's E-Nose breathprints compare to changes in their standard imaging scans and in biomarkers of MPM in their blood.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Aged 30-85 years
- •No history of thoracic cancer or extrathoracic cancer potentially involving pleural metastases (i.e., breast, gastric, colon, or pancreas cancer)
- •Recent diagnosis of MPM
- •Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study, and signed standard surgical consent for surgical resection
Exclusion Criteria
- •Aged \<30 or \>85 years at the first outpatient visit
- •History of thoracic or extrathoracic cancer that puts the subject at risk for pleural or pulmonary metastases
Outcomes
Primary Outcomes
Change of MPMspecific VOCs
Time Frame: up to 1 year
compared with imaging (using RECIST 1.1 and mRECIST).
Study Sites (7)
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