CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema
Phase 3
Completed
- Conditions
- Severe Acute Cardiogenic Pulmonary Edema
- Registration Number
- NCT00213681
- Lead Sponsor
- University Hospital, Rouen
- Brief Summary
To evaluate whether bilevel positive airway pressure more rapidly improves ventilation than continuous positive airway pressure (CPAP) in patients with acute pulmonary edema. CPAP is delivered via a simple device connected to oxygen.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- age > 16 yrs, acute onset of severe respiratory distress, bilateral rales and typical findings of congestion on chest radiograph
- breathing frequency of > 30/min, SpO2 >90%, use of accessory respiratory muscles
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Improvement in PaCO2 at the end of ventilation
- Secondary Outcome Measures
Name Time Method Blood gases, vital signs Time to transfer to medical ward Time to hospital discharge Endotracheal intubation, myocardial infarction and mortality during the first 24 hours Duration of the ventilation Easiness to use was evaluated by nurses Patients operational tolerance Complications of each ventilation mode