MedPath

Safety and Efficacy of the LMA Supreme When Inserted With Patients in the Prone Position

Conditions
Airway Obstruction
Interventions
Device: LMA Supreme
Registration Number
NCT03633942
Lead Sponsor
Laser Spine Institute
Brief Summary

This study is a non-randomized, observational, non-comparative prospective study to evaluate the safety, efficacy and performance of the LMA Supreme laryngeal mask airway when used according to the device's Instructions for Use.

Detailed Description

This study is a non-randomized, observational, non-comparative prospective study to evaluate the safety, efficacy and performance of the LMA Supreme laryngeal mask airway when used according to the device's Instructions for Use. During surgery, standard treatment will be applied, complemented with the recording of study parameters related to safety, efficacy and performance of the LMA Supreme laryngeal mask airway.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
1000
Inclusion Criteria
  • 18 to 70 years of age
  • American Society of Anesthesiology Classification (ASA) I-III patients
  • Fasting for 8 hours
  • Scheduled surgery with indication for laryngeal mask airway
Exclusion Criteria
  • Have contraindicating conditions
  • Have had radiotherapy to the neck involving the hypopharynx (risk of trauma, failure to seal effectively).
  • Have inadequate mouth opening to permit insertion
  • History of hiatal hernia
  • Scheduled for minimally invasive spine stabilization procedures such as Transforaminal Lumbar Interbody Fusion (TLIF), Anterior Cervical Discectomy and Fusion (ACDF) (all have neuromonitoring/general endotracheal intubation)
  • Scheduled for Joimax procedure (initial anesthetic is MAC)
  • Unable to safely position themselves prone with assistance
  • History of previous failed LMA Supreme placement
  • BMI greater than or equal to 53
  • Outside age or ASA range specified in inclusion criteria
  • Inability to comply with study requirements including follow-up

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Observational: LMA SupremeLMA SupremeAn appropriately sized LMA Supreme will be prepared by removing all air from the cuff while applying manual pressure. A water soluble non-local anesthetic containing lubricant gel will be applied to the fully deflated airway before insertion. A 1 cm column of the gel will be preloaded into the gastric port of the LMA Supreme for the Gel Test. The cuff will be inflated with a manometer to a pressure of approximately 30cm H2O. If a significant leak is detected, the cuff will be inflated in increments of 5cm H2O until a satisfactory seal is obtained. The final cuff pressure will be recorded. The lungs will then be gently inflated by applying manual pressure to the anesthesia circuit bag while observing the gel column in the LMA Supreme gastric port for movement.
Primary Outcome Measures
NameTimeMethod
The efficacy of the LMA Supreme device as assessed by measurement of ventilation on Case Report Form 1Intraoperative

Outcome being measured intraoperatively is the ease of manual ventilation via the LMA Supreme. Measuring, no air leaks, air leak / elevated airway pressure needed for adequate ventilation, removal and reinsertion needed to achieve adequate ventilation, no ventilation after 2 attempts (airway managed using alternative techniques

The efficacy of the LMA Supreme device as assessed by measurement of ease of swallowing on Case Report Form 2Preoperative and up to 4 weeks (+/- 5 days) postoperative

Outcome being measured preoperatively and at 4 weeks +/- 5 days is the Dysphagia (difficulty swallowing) Short Questionnaire. Measuring the ability to swallow (any difficulty in swallowing), incorrect swallowing (any coughing associated with swallowing), lump feeling (any lumps in the throat), involuntary loss of weight (any weight loss recently), Pneumonia (any bouts with pneumonia).

The efficacy of the LMA Supreme device as assessed by measurement of removal of the LMA Supreme Device on Case Report Form 1Intraoperative

Outcome being measured intraoperatively is any blood on the LMA upon removal. Measuring if there is minimal or no blood, blood covering less than one fourth of the LMA or blood on at least one half of the LMA surface.

The efficacy of the LMA Supreme device as assessed by measurement of any intraoperative episodes developing reporting outcomes on Case Report Form 1Intraoperative

Outcome being measured intraoperatively is did patient develop any intraoperative episodes of laryngospasm, hiccups, or coughing.

Secondary Outcome Measures
NameTimeMethod
Dysphagia Short QuestionnairePreoperative and up to 4 weeks postoperative (+/- 5 days).

Instrument used to measure difficulty swallowing (dysphagia).

Trial Locations

Locations (1)

Laser Spine Institute

🇺🇸

Tampa, Florida, United States

© Copyright 2025. All Rights Reserved by MedPath