Comparison of Lornoxicam and Etodolac on Edema, Trismus and Pain After Third Molar Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Edema after wisdom tooth extraction
研究概览
简要总结
Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction
详细描述
20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Bilateral mesioangular impacted lower third molar
- •Asymptomatic Third Molar (No history of infection)
- •Systemically Healthy Person
- •Person Between aged 18-30
排除标准
- •People who are pregnant and lactation process
- •People who had any systemic disease
- •People who are gastrointestinal problems
- •People who are sensitive to drugs used in study
- •Lower Third Molar associated with cysts and infections
研究组 & 干预措施
Etodolac
Etodolac, 400 mg tid per a day for four days
干预措施: Lornoxicam 8 Mg Oral Tablet (Drug)
Lornoxicam
Lornoxicam, 8 mg twice per day for four days
干预措施: Lornoxicam 8 Mg Oral Tablet (Drug)
结局指标
主要结局
Edema after wisdom tooth extraction
时间窗: 48 th hours
Edema lower third molar removal, Edema was evaluated by using reference line on the face
Pain after wisdom tooth extraction
时间窗: 2 th hours
Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)
Trismus after wisdom tooth extraction
时间窗: 48 th hours,
Trismus lower third molar removal, trismus was evaluated by using caliper
次要结局
- Pain after wisdom tooth extraction(48 th hours)
- Edema after wisdom tooth extraction(168 th hours)
- Trismus after wisdom tooth extraction(168 th hours)
研究者
Zulfikar Karabiyik
Research Assistant
Kutahya Health Sciences University