Lornoxicam Versus Etodolac After Third Molar Surgery

Phase 4

Completed

• Conditions: Edema; Pain, Acute; Trismus
• Interventions: Drug: Lornoxicam 8 Mg Oral Tablet

• Registration Number: NCT05679453
• Lead Sponsor: Kutahya Health Sciences University

Brief Summary

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

Detailed Description

20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours

Study Timeline

• Study Start: 2022-07-20
• Primary Completion: 2022-09-25
• Study Completion: 2022-09-29
• Study First Submitted: 2022-10-31
• Status Verified: 2022-12
• Study First Submitted QC: 2022-12-23
• Last Update Submitted: 2022-12-23
• Study First Posted: 2023-01-11
• Last Update Posted: 2023-01-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Bilateral mesioangular impacted lower third molar
• Asymptomatic Third Molar (No history of infection)
• Systemically Healthy Person
• Person Between aged 18-30

Exclusion Criteria

• People who are pregnant and lactation process
• People who had any systemic disease
• People who are gastrointestinal problems
• People who are sensitive to drugs used in study
• Lower Third Molar associated with cysts and infections

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Lornoxicam	Lornoxicam 8 Mg Oral Tablet	Lornoxicam, 8 mg twice per day for four days
Etodolac	Lornoxicam 8 Mg Oral Tablet	Etodolac, 400 mg tid per a day for four days

Primary Outcome Measures

Name	Time	Method
Edema after wisdom tooth extraction	48 th hours	Edema lower third molar removal, Edema was evaluated by using reference line on the face
Pain after wisdom tooth extraction	2 th hours	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)
Trismus after wisdom tooth extraction	48 th hours,	Trismus lower third molar removal, trismus was evaluated by using caliper

Secondary Outcome Measures

Name	Time	Method
Pain after wisdom tooth extraction	48 th hours	Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)
Edema after wisdom tooth extraction	168 th hours	Edema lower third molar removal, Edema was evaluated by using reference line on the face
Trismus after wisdom tooth extraction	168 th hours	Trismus lower third molar removal, trismus was evaluated by using caliper

Trial Locations

Locations (1)

Zülfikar Karabıyık; 🇹🇷 Kutahya, Turkey