Investigating effect of Spirulina dietary supplementation on COVID-19 disease outcomes in patients admitted to Intensive Care Units
Phase 2
Recruiting
- Conditions
- COVID-19.?????? ?????-19 ????? ??? ?? ?????? ??????????U07.1
- Registration Number
- IRCT20200720048139N1
- Lead Sponsor
- Islamic Azad University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 138
Inclusion Criteria
All covid-19 patients confirmed with PCR test admitted to the ICU are entered the trial
Exclusion Criteria
Age less than 18
Women during pregnancy and lactation
Consumers of supplements C, E, Omega 3, Antioxidants in the last 3 months
Patients with severe renal failure
Patients with liver failure last stage (cirrhosis)
Patients with uncontrolled hypertension
Patients who do not have a functioning gastrointestinal tract and have not been prescribed oral or intravenous nutrition
Patients with drug / food allergies
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL6. Timepoint: The first and 28th of the study. Method of measurement: Blood Sample method: ELISA ; sensivity 0.06 pg/ml.;ESR (Erythrocyte sedimentation rate). Timepoint: The first and 28th of the study. Method of measurement: Automated Modified Westergren.;CRP. Timepoint: The first and 28th of the study. Method of measurement: Blood sampling- ELISA.;Nutrition Status. Timepoint: the first and 28th of the study. Method of measurement: Nutric-score Questionnaire.;Fever. Timepoint: Daily. Method of measurement: Digital Thermometer.;O2 SATURATION. Timepoint: Duration the stay in ICU. Method of measurement: Pulse Oxymeter.
- Secondary Outcome Measures
Name Time Method Duration of Stay in ICU. Timepoint: Since the first day till end of stay in ICU. Method of measurement: OBSERVATION.;Ventilator Free days. Timepoint: During the stay in ICU. Method of measurement: Observation.;Mortality Rate. Timepoint: During the stay in ICU. Method of measurement: Observation.