CTRI/2024/09/074405尚未招募2 期
Role of Second generation antipsychotic on level of inflammatory markers in female Schizophrenia patients-A Comparative study.
Institute of Psychiatry1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年9月30日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To measure the inflammatory markers like IL-6 CRP Serum Ferritin in female schizophrenia patients and its relation with Schizophrenia.
研究概览
简要总结
To determine the role of antipsychotics in female Schizophrenia on the levels of inflammatory markers which is known to have been increased in Schizophrenia .In this study two groups of female Schizophrenia patients will be given second generation antipsychotics like Olanzapine and Risperidone .The two groups will be compared based on the change of level of inflammatory markers after the antipsychotic treatment for 6 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.All females cases fulfilling the diagnosis of schizophrenia according to criteria of ICD 11 and DSM-
- •2.Schizophrenia patients (female) who have been off psychotropic medication voluntarily or drug naive patients.
- •3.Age group 18-45years 4.Patient giving informed consent.
排除标准
- •1.Male schizophrenia patients.
- •2.Schizoaffective diagnosed cases.
- •3.Patients not giving informed consent.
- •4.History of any other neurodegenerative disorder.
- •5.History of epilepsy and head injury.
- •6.History of recent steroid use or iron supplement.
- •7.Female schizophrenia patients with increased triglycerides and blood sugar.
结局指标
主要结局
To measure the inflammatory markers like IL-6 CRP Serum Ferritin in female schizophrenia patients and its relation with Schizophrenia.
时间窗: 6 weeks
次要结局
- To measure the inflammatory markers IL-6 CRP Serum Ferritin after treatment with antipsychotics.(6 weeks after treatment with antipsychotics.)
研究者
Dr RINCHEN CHOPHEL BHUTIA
Institute of psychiatry IPGME&R SSKM hospital
研究点 (1)
Loading locations...
相似试验
已完成
不适用
LRFN5 and OLFM4 in SchizophreniaNCT07434388Elazığ Mental Health and Diseases Hospital60
尚未招募
Phase 3 4
Mitophagy-targeted Intervention for Negative symptoms and cognitive Deficits in Schizophrenia with Urolithin ACTRI/2025/10/095887Department of Psychiatry National Institute of Mental Health and Neuro Sciences (NIMHANS)80
招募中
4 期
Safety and pharmacokinetics of antipsychotics in children 2: Studying TDM in an RCTAutism spectrum disorder2024-511568-96-00Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)280
招募中
4 期
Biomarkers in clozapine-responding schizophreniaSchizophrenia2024-515338-34-01Psykiatrisk Center Glostrup200
已完成
不适用
LRFN5 and OLFM4 in Schizoaffective DisorderSchizoaffective DisorderNCT07447960Elazığ Mental Health and Diseases Hospital110