STrain and support in Early Pregnancy: Onward Neonatal Epigenetic effects (STEP ONE)
- Conditions
- Pregnant women undergoing amniocentesis due to medical reasons
- Registration Number
- DRKS00005741
- Lead Sponsor
- Zentralinstitut für Seelische Gesundheit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 125
Inclusion Criteria
pregnant women, amniocentesis for medical reasons
Exclusion Criteria
severe genetic findings, severe disability of the child, insufficient german language, impaired ability to consent, multiples
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relationship between strain, psychological features and social support of the pregnant women (measured with questionnaires and interview) and epigenetic features of the infant (DNA methylation in cells of amniotic fluid and cord blood).
- Secondary Outcome Measures
Name Time Method