Thoracic Point of Care Ultrasound on Initial Management of Upper Gastrointestinal Bleeding
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- B-type lines on thoracic point-of-care ultrasound in patients with UGIB.
研究概览
简要总结
Upper Gastrointestinal bleeding (UGIB) is a medical emergency and the most common cause of hospitalization associated with digestive disease. Proper initial resuscitation is the first step in the management of UGIB patients. Today, modern pulmonary ultrasound is used in different clinical settings, such as intensive care, emergency medicine and/or traumatology. In the last years, the use of this has been standardized both in internal medicine and in pulmonary medicine. The primary objective is to describe the findings of pulmonary ultrasound and its relationship with severity in patients with UGIB. The investigators will include all patients with UGIB. A pulmonary and vena cava ultrasound will be performed on admission to the emergency room, 10 minutes prior to endoscopy and 24 hours after having performed the endoscopy.
The use of thoracic point-of-care ultrasound (TPOCUS) has been standardized in both internal and pulmonary medicine. There is a concern about the role of TPOCUS useful as a severity prognostic tool in patients with UGIB.
The team proposes that TPOCUS is a severity prognostic tool in UGIB patients.
Main Outcome: To describe the findings of TPOCUS in patients with variceal and non-variceal UGIB.
Secondary Objectives:
- Correlate the presence of B-type lines on TPOCUS with mean arterial pressure in UGIB patients.
- Correlate the inferior vena cava diameter with the Model for End-stage Liver Disease scale in UGIB patients.
- Correlate the inferior vena cava diameter with the 48 hours post-admission mortality of UGIB patients.
Authors design a prospective, longitudinal, descriptive study to identify the findings of TPOCUS in patients with variceal and non-variceal UGIB. Patients will be included in the study since May 15th through October 30th 2019, admitted to the University Hospital, "Dr. José E. González", Universidad Autónoma de Nuevo León.
详细描述
Inclusion criteria:
- Patients with a diagnosis of UGIB documented by endoscopy.
- Any gender.
- Over 18 years old.
Exclusion criteria:
- Patients with UGIB previously treated in other hospitals.
- Patients under 18 years of age.
- Patients with suspected UGIB who did not undergo endoscopy.
- Pregnant.
- Patients with chronic obstructive pulmonary disease.
- Patients with interstitial lung disease.
- Patients with pleural effusion at the time of admission to the emergency room.
- Refusal to participate in the protocol.
Method The investigators will study all patients who come to the emergency room of the hospital due to suspicion of UGIB (melena, hematemesis, vomiting in coffee grounds and hematochezia with hemodynamic instability). These patients will undergo a pulmonary and vena cava ultrasound.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age, more than 17 years old.
- •Patients diagnosed with UGIB.
- •Any etiology of the UGIB.
排除标准
- •Patients with UGIB previously treated in other hospitals.
- •Patients with UGIB with Blatchford scale less than 2 points.
- •Pregnant women.
- •Refusal to participate in the protocol.
结局指标
主要结局
B-type lines on thoracic point-of-care ultrasound in patients with UGIB.
时间窗: 48 hours
The number of B-type lines measured by thoracic point-of-care ultrasound in patients with variceal and non-variceal UGIB at 48 hours.
Diameter of inferior vena cava on thoracic point-of-care ultrasound in patients with UGIB.
时间窗: 48 hours
The diameter in centimeters of inferior vena cava measured by thoracic point-of-care ultrasound in patients with variceal and non-variceal UGIB at 48 hours.
次要结局
- B-type lines and mean arterial pressure on UGIB patients(48 hours)
- Inferior vena cava diameter and Model for End-stage Liver Disease on UGIB patients(48 hours)
- Inferior vena cava diameter and 48 hours mortality in UGIB patients.(48 hours)
研究者
Dr. med. Hector Eloy Tamez Perez
Clinical Professor
Hospital Universitario Dr. Jose E. Gonzalez