NCT04604717已完成不适用
Effect of Exercise Training on Salivary Immunoglobulin A in Patients With Chronic Obstructive Pulmonary Disease
Bayside Health2 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2014年4月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Change in Salivary Immunoglobulin A levels
研究概览
简要总结
The purpose of this study is to determine whether whole body exercise training alters the immunity in the lungs of people with COPD and reduces the incidence of chest infections over the longer term.
详细描述
Patients will undertake an 8 weeks pulmonary rehabilitation program of exercise and education. Those who decline to take part in pulmonary rehabilitation will have the same outcome measures collected at the same timepoints.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of COPD (FEV1/FVC < 70), smoking Hx of minimum of 10 pack years
排除标准
- •Diagnosis of asthma, bronchiectasis, attendance at pulmonary rehabilitation within last 12 months, exacerbation of COPD within last 4 weeks
研究组 & 干预措施
Pulmonary rehabilitation
Experimental
8 weeks of pulmonary rehabilitation (twice weekly training) Exercise and education sessions accompanied by home exercise program
干预措施: Pulmonary rehabilitation (Other)
Control group
No Intervention
Usual medical treatment for 8 week period
结局指标
主要结局
Change in Salivary Immunoglobulin A levels
时间窗: Change over 8 weeks
SIgA
次要结局
- Change in circulatory inflammatory markers(Change over 8 weeks)
- Change in physical activity levels(Change over 8 weeks)
- Health status(Change over 8 weeks)
- Exercise capacity (6MWT)(Change over 8 weeks)
- Number of acute exacerbations(12 months)
研究者
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Does exercise change how many immune cells are in the blood during different stages of myeloma?Multiple myelomaCancerISRCTN10197225niversity of Bath23
Unknown
4 期
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) PhenotypeObstructive Chronic Pulmonary DiseaseEmphysemaChronic BronchitisNCT01431625Hospitales Universitarios Virgen del Rocío30
已完成
不适用
Exercise-induced Effects on Immune Parameters in Healthy ParticipantsHealthyNCT05826496Per thor Straten59
Unknown
不适用
Cancer Survivors Acute Exercise Response 1Neoplasms MalignantNCT03903848University of Houston18
已完成
不适用
The Immune Function Intervention TrialImmune ResponseNCT00548990National Institute on Aging (NIA)150