Study of effectiveness of Vyoshadi Vati given with and without Surasasidhha taila nasya for 21 days in Allergic rhinitis patients.

Not yet recruiting

Brief Summary: Allergic rhinitis is the common disease found in todayâ€™s population. In India, 20% to 30% of the population is suffering from allergic rhinitis. Changes in lifestyle, food habits and pollution contribute to the allergic conditions and lead them to chronic stages. Modern sciences treat allergic rhinitis with antihistamines and steroids given orally or nasally. But these drug have many side effects and the recurrence of disease is also noted. So there is need for the safe, effective and easily available quality drug. Allergic rhinitis is characterized by paroxysmal sneezing, nasal obstruction, watery rhinorrhoea and nasal irritation. Vyoshadi vati has been previously studied and proven to be effective in pratishyay disease. As the symptoms of allergic rhinitis are similar to those of vataj pratishyay disease described in ayurveda, Vyoshadi vati can be given to treat allergic rhinitis. Surasa i.e. Ocimum sanctum has anti allergic properties according to modern studies and is also effective in pratishyay according to ayurveda. Hence Surasasidhha tailya nasya drops given through nasal route is taken for research study. The efficacy of Vyoshadi vati given with and without Surasasidhha taila nasya is to be studied and compared in this clinical trial.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

Known cases of chronic non specific infective rhinitis like hypertrophic rhinitis, atrophic rhinitis, rhinitis sicca, rhinitis caseosa, malignant granuloma.
Known cases of chronic specific infective rhinitis like syphilis, leprosy, T.B., lupus vulgaris, rhinosporidiosis, rhinoscleroma, fungal infections and leishmaniasis.
Patients with known case of systemic illnesses like hypertension, diabetes mellitus, HIV and HbSAg. 4.
Patients with DNS, nasal polyps, tumors, malignancy of any kind.
Pregnant women.

Primary Outcome Measures

Name	Time	Method
To compare add on effects of Surasasidhha taila nasya 2 drops in each nostril at morning to Vyoshadi vati 250 mg 2 tablets twice daily after meal for 21 days in Allergic rhinitis patients of age group 18 years to 50 years.	21 days with follow up on 8th, 15th, 22nd day and 1 month after completion of the treatment.

Secondary Outcome Measures

Name	Time	Method
To observe the adverse effects of the drugs if any.	21 days with follow up on 8th, 15th, 22nd day and 1 month after completion of the treatment.

Locations (1): PDEAS ayurved rugnalaya and sterling multi speciality hospital, nigdi, pradhikaran, pune
🇮🇳
Pune, MAHARASHTRA, India
PDEAS ayurved rugnalaya and sterling multi speciality hospital, nigdi, pradhikaran, pune
🇮🇳Pune, MAHARASHTRA, India
Dr Shubhangi Suresh Avhad
Principal investigator
8308307616
avhad.shubhangi00@gmail.com