Heart Rate Variability as a Predictor of Ischemic Heart Disease

Completed

• Conditions: Acute Coronary Syndrome
• Interventions: Other: Heart rate variability

• Registration Number: NCT02959788
• Lead Sponsor: University of Iowa

Brief Summary

Identification of patients who are at highest risk for heart attack is an important task for emergency medicine physicians. Currently, physicians use a variety of different scoring systems to stratify their risk for having a heart attack. Heart rate variability (HRV) is a measure derived from noninvasive cardiac monitoring. This data is collected from a simple, non-invasive chest strap during a 10-minute recording session. The purpose of this proposal is to collect heart rate variability data on patients admitted to the emergency department with chest pain. The intent is to measure the association between heart rate variability and the various risk stratification scoring systems for chest pain.

Detailed Description

Identification of patients who are at highest risk for heart attack is an important task for emergency medicine physicians. Currently, physicians use a variety of different scoring systems to stratify their risk for having a heart attack. Heart rate variability (HRV) is a measure derived from noninvasive cardiac monitoring. This data is collected from a simple, non-invasive chest strap during a 10-minute recording session. The purpose of this proposal is to collect heart rate variability data on patients admitted to the emergency department with chest pain. The intent is to measure the association between heart rate variability and the various risk stratification scoring systems for chest pain.

The investigators propose to enroll patients admitted to the emergency department with chest pain. In addition to HRV data, clinical risk factors will be obtained, using validated clinical risk scoring systems. The team will follow patient's clinical course in order to include information about the determined cause of chest pain. The goal is to understand how HRV can augment common risk stratification scoring systems for patient presenting to the ED with chest pain.

Study Timeline

• Study Start: 2016-04
• Primary Completion: 2016-08
• Study Completion: 2016-08
• Study First Submitted: 2016-11-07
• Study First Submitted QC: 2016-11-07
• Study First Posted: 2016-11-09
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-10
• Last Update Posted: 2017-02-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• Chest pain in ED

Exclusion Criteria

• STEMI
• Prisoners
• Pregnant women
• Unable to consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Chest pain patients	Heart rate variability	All patients who present to the ED with chest pain.

Primary Outcome Measures

Name	Time	Method
Major adverse cardiac events	30 days

Secondary Outcome Measures

Name	Time	Method
HEART score	1 day
Coronary heart disease risk factors	1 day

Trial Locations

Locations (1)

University of Iowa Hospitals and Clinics; 🇺🇸 Iowa City, Iowa, United States