Community-based Microalbuminuria Screening in Patients With Hypertension
- Conditions
- HypertensionMicroalbuminuria
- Registration Number
- NCT03596840
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Brief Summary
This study evaluates the effectiveness of different anti-hypertensive drugs on patients with hypertension and microalbuminuria.
- Detailed Description
This is a a real world registry study. All patients with hypertension in community hospitals in China will be eligible . Patient demographics, medical history, clinical characteristics, physical examination, laboratory tests (including UCAR, blood routine, urine routine, blood biochemistry, and ECG), antihypertensive drugs (including: ACEI/ ARB, thiazide diuretics, CCB, beta-blockers, alpha-blockers, and other antihypertensive drugs used in real-life clinical practice in other communities.) will be recorded. All patients are anticipated to be followed up for 12-month. Effectiveness of different antihypertensive medications on Urine Albumin-to-Creatinine Ratio (UACR) will be evaluted.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 3000
- Patients with essential hypertension;
- Urinary albumin/creatinine ratio in random urine samples is 30-300 mg/g
- Age >=18
- Understand and sign informed consent
- This is a real-world registry study and does not set exclusion criteria
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Urine Albumin-to-Creatinine Ratio (UCAR) 12 months Differences in UCAR between with ACEI/ARB and without ACEI/ARB
- Secondary Outcome Measures
Name Time Method Combined endpoints: re-admission, cardiovascular events, and all-cause mortality 12 months Differences in Combined endpoints between with ACEI/ARB and without ACEI/ARB