Effectiveness of Different Antihypertensive Medications on Urine Albumin-to-Creatinine Ratio (UACR) in Community Hypertensive Patients With Microalbuminuria
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 3,000
- 主要终点
- Urine Albumin-to-Creatinine Ratio (UCAR)
研究概览
简要总结
This study evaluates the effectiveness of different anti-hypertensive drugs on patients with hypertension and microalbuminuria.
详细描述
This is a a real world registry study. All patients with hypertension in community hospitals in China will be eligible . Patient demographics, medical history, clinical characteristics, physical examination, laboratory tests (including UCAR, blood routine, urine routine, blood biochemistry, and ECG), antihypertensive drugs (including: ACEI/ ARB, thiazide diuretics, CCB, beta-blockers, alpha-blockers, and other antihypertensive drugs used in real-life clinical practice in other communities.) will be recorded. All patients are anticipated to be followed up for 12-month. Effectiveness of different antihypertensive medications on Urine Albumin-to-Creatinine Ratio (UACR) will be evaluted.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with essential hypertension;
- •Urinary albumin/creatinine ratio in random urine samples is 30-300 mg/g
- •Age >=18
- •Understand and sign informed consent
排除标准
- •This is a real-world registry study and does not set exclusion criteria
结局指标
主要结局
Urine Albumin-to-Creatinine Ratio (UCAR)
时间窗: 12 months
Differences in UCAR between with ACEI/ARB and without ACEI/ARB
次要结局
- Combined endpoints: re-admission, cardiovascular events, and all-cause mortality(12 months)
研究者
Xuejuan Jin
Associate Professor
Shanghai Zhongshan Hospital