Comparison of Premixed vs Sequential Administration of Fentanyl as an Adjuvant to Low dose Intrathecal Hyperbaric Bupivacaine in Lower Segment Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.To compare the hemodynamic parameters between premixed and sequential group.
研究概览
简要总结
Hyperbaric Bupivacaine is the most commonly used local anesthetic for spinal anesthesia.
As it is heavier than CSF, it generally settles down. Giving low dose of Hyperbaric Bupivacaine will reduce the incidence of Hypotension. and combining it with Fentanyl, which is an opioid will prolong the effect and duration of anesthesia and will provide better analgesia. Also, it will be good for the Parturients as low dose of bupivacaine is used (7.5mg)
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.American Society of Anaesthesiologists (ASA) physical status I or II undergoing Lower Segment Cesarean Section.
- •2.Patient between the age group of 18-40 years.
排除标准
- •1.Patient with contraindication for spinal anaesthesia.
- •2.Height less than 150 cms.
- •3.Patient having severe pregnancy induced hypertension (PIH), intrauterine deaths or unknown fetal anomaly.
- •4.Patients allergic to any medications.
- •6.Patients with associated liver/renal/cardiac/pulmonary disease.
结局指标
主要结局
1.To compare the hemodynamic parameters between premixed and sequential group.
时间窗: Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes
2.To compare the onset and duration of sensory block between both group.
时间窗: Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes
3.To compare the onset and duration of motor block between both group.
时间窗: Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes
次要结局
- 1. To record APGAR score at 1 min and 5 min respectively(2. To record any complications if any)