Comparison of Premixed vs Sequential Administration of Fentanyl as an Adjuvant to Low dose Intrathecal Hyperbaric Bupivacaine in Lower Segment Cesarean Section

Not yet recruiting

• Conditions: Other complications of spinal andepidural anesthesia during pregnancy,

• Registration Number: CTRI/2021/09/036325
• Lead Sponsor: Teerthanker Mahaveer Medical College and Research centre Moradabad UP

Brief Summary

Hyperbaric Bupivacaine  is the most commonly used local anesthetic for spinal anesthesia.

As it is heavier than CSF, it generally settles down. Giving low dose of Hyperbaric Bupivacaine will reduce  the incidence of Hypotension. and combining it with Fentanyl, which is an opioid will prolong the effect and duration of anesthesia and will provide better analgesia. Also, it will be good for the Parturients as low dose of bupivacaine is used (7.5mg)

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-07-09
• Study Start: 2021-10-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• 1.American Society of Anaesthesiologists (ASA) physical status I or II undergoing Lower Segment Cesarean Section.
• 2.Patient between the age group of 18-40 years.

Exclusion Criteria

• 1.Patient with contraindication for spinal anaesthesia.
• 2.Height less than 150 cms.
• 3.Patient having severe pregnancy induced hypertension (PIH), intrauterine deaths or unknown fetal anomaly.
• 4.Patients allergic to any medications.
• 6.Patients with associated liver/renal/cardiac/pulmonary disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To compare the hemodynamic parameters between premixed and sequential group.	Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes
2.To compare the onset and duration of sensory block between both group.	Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes
3.To compare the onset and duration of motor block between both group.	Hemodynamic parameters at 5,10,15,20,25,30,40,50,60,70,80 minutes

Secondary Outcome Measures

Name	Time	Method
1. To record APGAR score at 1 min and 5 min respectively	2. To record any complications if any

Trial Locations

Locations (1)

Teerthanker Mahaveer Medical College; 🇮🇳 Moradabad, UTTAR PRADESH, India

Teerthanker Mahaveer Medical College

🇮🇳Moradabad, UTTAR PRADESH, India

Ashay Jain

Principal investigator

8770995726

aashayjain142@gmail.com