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Study of Sitagliptine/ Metformin table In-Vivo Bioequivalence in healthy volunteers

Not Applicable
Conditions
In this study the bioequivalence of test and brand of Linagliptin tablets 5mg will evaluated..
Registration Number
IRCT20200105046010N12
Lead Sponsor
Razak Pharma
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
24
Inclusion Criteria

General health (liver, heart, kidney)
Body Mass Index (BMI) between 18-28
Informed consent
Age between 18-60
Both male and female

Exclusion Criteria

Smoking
Hypersensitivity to the drug
Alcohol & Drug addiction
Pregnancy

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Determination of blood drug concentration. Timepoint: Sampling times in this study will be 0, 1, 2, 2:30, 3, 3:20, 3:40, 4, 4:20, 4: 40, 5, 6, 8, 10, 12, 24, 48, 72 hours. Method of measurement: Liquid Chromatography with tandem mass spectroscopy detector.
Secondary Outcome Measures
NameTimeMethod
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