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Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth (PIGO)

Phase 3
Registration Number
CTRI/2008/091/000227
Lead Sponsor
AIIMS
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

Age: 5-15 yr
Started on PHT within 1 mo of enrollment

Exclusion Criteria

Not willing to participate
On other folic acid antagonists e.g. anti-neoplastic drugs for >/= 2 wks during last 3 mo
Pre-existing gingival over-growth due to other cause

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Occurrence of any grade of overgrowth in 2 groups after 6 mo of phenytoin therapyTimepoint: 6 mo
Secondary Outcome Measures
NameTimeMethod
Occurrence of grade > 2 hyperplasia at the end of 6 moTimepoint: 6 mo
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