comparison of the effects of platelet-rich plasma, platelet-rich fibrin and methylprednisolone injections in the treatment of knee arthrosis.
Phase 3
Recruiting
- Conditions
- knee osteoarthritis.Osteoarthritis of knee
- Registration Number
- IRCT20240223061090N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients based on ACR (American college of rheumatology) radiological criteria with knee Grade I, II and III osteoarthritis
Exclusion Criteria
Patients who are breastfeeding or pregnant
They have rheumatoid arthritis or severe heart disease.
Have a skin infection at the injection site
Be a consumer of immunosuppressive drugs or anticoagulants such as warfarin and heparin
A history of bleeding or a description of clotting disorders or anemia
Have current back pain with spreading to lower limbs
Have a history of knee surgery in the last three months
Have an active infection or malignancy within the previous 6 months
Substance abuse
Intra-articular corticosteroid injections in the last 2 months or hyaluronic acid in the last 6 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method