Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome
Not Applicable
- Conditions
- PCOS
- Interventions
- Procedure: IVF/ICSI
- Registration Number
- NCT03527979
- Lead Sponsor
- Ain Shams University
- Brief Summary
the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 88
Inclusion Criteria
- age between 25 and 35
- patients with established PCOS
- history at least one year infertility
- no response to clomiphene citrate for at least three cycles
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Exclusion Criteria
- history of previous IVF/ICSI
- chronic disease such as thyroid disorder and DM
- infertility due to sever male factor
- sever endometriosis
- infertility due to uterine factor such as multiple fibroid
- body mass index > 30
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description PCOS women without history of drilling IVF/ICSI - PCOS women with history of LOD before IVF/ICSI IVF/ICSI -
- Primary Outcome Measures
Name Time Method clinical pregnancy rate confirmed by b-hcg and visualizations of gestational sac by ultrasound 3 months Pregnancy confirmed by b-hcg and visualization of gestational sac by ultrasound
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ain Shams university
🇪🇬Cairo, Egypt