NCT03527979Unknown不适用
Effect of Laparoscopic Ovarian Drilling on the Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- clinical pregnancy rate confirmed by b-hcg and visualizations of gestational sac by ultrasound
研究概览
简要总结
the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age between 25 and 35
- •patients with established PCOS
- •history at least one year infertility
- •no response to clomiphene citrate for at least three cycles
排除标准
- •history of previous IVF/ICSI
- •chronic disease such as thyroid disorder and DM
- •infertility due to sever male factor
- •sever endometriosis
- •infertility due to uterine factor such as multiple fibroid
- •body mass index > 30
研究组 & 干预措施
PCOS women without history of drilling
Active Comparator
干预措施: IVF/ICSI (Procedure)
PCOS women with history of LOD before IVF/ICSI
Active Comparator
干预措施: IVF/ICSI (Procedure)
结局指标
主要结局
clinical pregnancy rate confirmed by b-hcg and visualizations of gestational sac by ultrasound
时间窗: 3 months
Pregnancy confirmed by b-hcg and visualization of gestational sac by ultrasound
次要结局
未报告次要终点
研究者
rabab adel kamal
ob/gyn resident
Ain Shams University
研究点 (1)
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