Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Complete blood picture
研究概览
简要总结
This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.
详细描述
This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.
Participants will be assigned into 3 groups equal in number (group A, group B, group C)
Group A (Respiratory Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive respiratory training for 6 weeks.
Group B : (Aerobic Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive aerobic training for 6 weeks
Group C : (control group) :It will include 20 patients of both sexes, recovered from COVID-19 infection on medical drugs only will receive no exercise as control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients recovered from COVID -19 infection.
- •Patients with body mass index 25 - 35 kg/m2
- •Patients previously diagnosed with chest symptoms of COVID- 19 infection.
- •Patients' body temperature less than 37.5
- •Blood oxygen saturation ≥95%
排除标准
- •Patients with Myocardial infarction
- •Patients with diabetes.
- •Patients with autoimmune disease.
- •Patients with positive COVID -19 infection.
- •Patients with previous chest diseases
- •a heart rate of >100 bpm
- •a blood pressure of <90/60 mmHg or >140/90 mmHg
- •a blood oxygen saturation of ≤95%
- •other diseases that are not suitable for exercise (osteoarthritis knee - stroke patients, etc)
结局指标
主要结局
Complete blood picture
时间窗: change from baseline at 6 weeks
A venous blood sample will be taken to be analyzed in the laboratory
Arterial blood gases
时间窗: change from baseline at 6 weeks
arterial blood sample will be assessed
6-minute walk Distance
时间窗: change from baseline at 6 weeks
patient will be instructed to walk as fast as long as possible, in a 30 meters obstacle- free corridor, limited by turnaround cones. Standardized verbal encouragement will be given every minute. After 6 min, patient will be instructed to stop, and the total distance will be measured, rounding to the nearest meter.
Breath-hold test
时间窗: change from baseline at 6 weeks
A rough index of cardiopulmonary reserve measured by the length of time that a person can voluntarily stop breathing; normal duration is 30 seconds or longer; diminished cardiac or pulmonary reserve is indicated by a duration of 20 seconds or less.
Oxygen saturation
时间窗: change from baseline at 6 weeks
Percentage of haemoglobin saturated with oxygen measured by pulse oximeter
Borg Dyspnea Scale score
时间窗: change from baseline at 6 weeks
It is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient during six minute walk test
次要结局
- Maximum oxygen consumption(change from baseline at 6 weeks)
研究者
Heba Ahmed Ali Abdeen
Assistant Professor
Cairo University