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Clinical Trials/NCT04613050
NCT04613050
Completed
Not Applicable

Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients

Cairo University1 site in 1 country80 target enrollmentJuly 2, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Covid 19 Infection
Sponsor
Cairo University
Enrollment
80
Locations
1
Primary Endpoint
Complete blood picture
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.

Detailed Description

This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups. Participants will be assigned into 3 groups equal in number (group A, group B, group C) Group A (Respiratory Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive respiratory training for 6 weeks. Group B : (Aerobic Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive aerobic training for 6 weeks Group C : (control group) :It will include 20 patients of both sexes, recovered from COVID-19 infection on medical drugs only will receive no exercise as control group.

Registry
clinicaltrials.gov
Start Date
July 2, 2020
End Date
October 30, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Heba Ahmed Ali Abdeen

Assistant Professor

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patients recovered from COVID -19 infection.
  • Patients with body mass index 25 - 35 kg/m2
  • Patients previously diagnosed with chest symptoms of COVID- 19 infection.
  • Patients' body temperature less than 37.5
  • Blood oxygen saturation ≥95%

Exclusion Criteria

  • Patients with Myocardial infarction
  • Patients with diabetes.
  • Patients with autoimmune disease.
  • Patients with positive COVID -19 infection.
  • Patients with previous chest diseases
  • a heart rate of \>100 bpm
  • a blood pressure of \<90/60 mmHg or \>140/90 mmHg
  • a blood oxygen saturation of ≤95%
  • other diseases that are not suitable for exercise (osteoarthritis knee - stroke patients, etc)

Outcomes

Primary Outcomes

Complete blood picture

Time Frame: change from baseline at 6 weeks

A venous blood sample will be taken to be analyzed in the laboratory

Arterial blood gases

Time Frame: change from baseline at 6 weeks

arterial blood sample will be assessed

6-minute walk Distance

Time Frame: change from baseline at 6 weeks

patient will be instructed to walk as fast as long as possible, in a 30 meters obstacle- free corridor, limited by turnaround cones. Standardized verbal encouragement will be given every minute. After 6 min, patient will be instructed to stop, and the total distance will be measured, rounding to the nearest meter.

Breath-hold test

Time Frame: change from baseline at 6 weeks

A rough index of cardiopulmonary reserve measured by the length of time that a person can voluntarily stop breathing; normal duration is 30 seconds or longer; diminished cardiac or pulmonary reserve is indicated by a duration of 20 seconds or less.

Oxygen saturation

Time Frame: change from baseline at 6 weeks

Percentage of haemoglobin saturated with oxygen measured by pulse oximeter

Borg Dyspnea Scale score

Time Frame: change from baseline at 6 weeks

It is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient during six minute walk test

Secondary Outcomes

  • Maximum oxygen consumption(change from baseline at 6 weeks)

Study Sites (1)

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