Use of Discarded Surgery Human Tissue Specimens for Basic Science Research

Recruiting

• Conditions: Vascular Calcification; Osteoblast

• Registration Number: NCT04753593
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Although it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to consider new approaches to clinical management of patients with such conditions. It is in this context that the investigators need to use residual human tissue fragments resulting from surgery which are not intended to be used for clinical-biological management of patients. The use of these pseudonymised human tissues will allow the investigators to conduct in vitro cell culture experiences.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-02-11
• Study First Submitted QC: 2021-02-11
• Study First Posted: 2021-02-15
• Study Start: 2021-03-16
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-09
• Last Update Posted: 2023-02-10
• Primary Completion: 2026-02
• Study Completion: 2026-02

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie
• patients who will be beforehand informed
• patients who will not be opposed to this study.

Exclusion Criteria

• HIV and hepatitis positive patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success in establishment of Cell Culture Systems from discarded surgery specimens	5 years	Success in establishment of Cell Culture Systems from discarded surgery specimens

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France