The Effects Of Femur On The Resting Myoelectrical Activity Of Contralateral Adductor Muscle During Unilateral Lower Extremity Vibration: Bone Myoregulation Reflex
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Vibration-induced contralateral muscle electrical activity
研究概览
简要总结
The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.
This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.
详细描述
A total of 20 voluntaries are planned to include in this study.
Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.
The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.
Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age: 20-40 yrs
- •Gender: Male
- •Volunteer
- •Healthy status: Patients having hypoesthesia in his leg and Healthy subjects
- •Dominant hand:Right-handed
排除标准
- •Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),
- •Systemic diseases (cardiovascular, endocrine, infections etc),
- •Myopathy-tendinopathy
- •Lower limb joint disease
- •Obesity (BMI >30 kg/m2)
- •Professional sportsman
- •Male doing regular sports activities
- •Skin disease in lower limb
- •Non-cooperative subject
- •Hemolysis of blood sample
结局指标
主要结局
Vibration-induced contralateral muscle electrical activity
时间窗: 3 month
次要结局
未报告次要终点
研究者
Ilhan Karacan, Clinical Associated Professor
ILHAN KARACAN
Bagcilar Training and Research Hospital