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Clinical Trials/ISRCTN30405954
ISRCTN30405954
Completed
未知

A feasibility trial evaluating mobility and strength training with and without protein supplements in pre-frail/frail older adults with low protein intake

niversity of Oxford0 sites50 target enrollmentOctober 18, 2022

Overview

Phase
未知
Intervention
Not specified
Conditions
Pre-frail/frail older adults with low protein intake
Sponsor
niversity of Oxford
Enrollment
50
Status
Completed
Last Updated
last year

Overview

Brief Summary

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/39139274/ (added 14/08/2024)

Registry
who.int
Start Date
October 18, 2022
End Date
July 31, 2024
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Aged 65 years and older
  • 2\. Frail (at least three criteria) or pre\-frail (one or two criteria) as defined by the Fried Frailty criteria and must include slow walking speed (or difficulty walking).
  • 3\. Low protein intake (\<1 g protein/kg body weight/day) measured by the average of two 24\-hour dietary recall assessments.
  • 4\. Willing and able to provide informed consent to participate

Exclusion Criteria

  • 1\. Dementia or cognitive impairment (defined as an Abbreviated Mental Test score of 6 or less)
  • 2\. Inability to walk 3 m without assistance (walking aid permitted)
  • 3\. Unable to follow verbal instructions which would make participation in the exercise group impractical including severe hearing impairment not corrected by a hearing aid or inability to follow simple safety instructions (e.g. English comprehension)
  • 4\. Living in a residential care or nursing home
  • 5\. Pre\-existing diagnosis of:
  • 5\.1\. Stroke in the last 6 months
  • 5\.2\. Parkinson’s Disease
  • 5\.3\. Acute, unstable physical illness that would make participation in the exercise programme unsafe
  • 5\.4\. Dysphagia or swallowing problems that requires a modified diet
  • 5\.5\. Type 1 diabetes or Type 2 diabetes on insulin

Outcomes

Primary Outcomes

Not specified

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