Project CP2: Recruiting, Assessment, and Biobanking in the clinical research unit 256 with the title Mechanisms of Disturbed Emotion Processing in Borderline-Personality Disorder

• Conditions: F60.31; F43.1; Post-traumatic stress disorder

• Registration Number: DRKS00010146
• Lead Sponsor: Zentralinstitut für Seelische Gesundheit, Universität Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-03-16
• Study Completion: 2018-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 1264

Inclusion Criteria

Current Borderline Personality disorder:
min. 5 criteria IPDE (International Personality Disorder Examination);

Remitted Borderline Personality disorder:
max. 3 criteria IPDE about the last 2 years and min. 5 criteria at an earlier time point, as diagnosed by IPDE;

Posttraumaticstress Disorder (PTSD):
PTSD according to DSM-IV (SCID I); sexual abuse during childhood according to Childhood Trauma Questionnaire (CTQ);

Fibromyalgia: Criteria of the American College of Rheumatology (Wolfe et al., 2010);

Healthy Controlls:
No psychiatric Axis I disorder according life span; no BPD (SCID I and IPSE);

Exclusion Criteria

- psychotropic medication
- lifetime diagnosis schizophrenia or bipoloar I disorder
- substance dependence within two years prior to study, current substance abuse (veryfied by negative urine drug screening)
- pregnancy
- history of epilepsy, brain trauma, brain tumor, or other significant neurological or medical condition

For imaging studies, additionally:
- metal implants or electric implants that cannot be removed
- claustrophobia

Study & Design

• Study Type: observational
• Study Design: Not specified