Spectrum Analysis of Endobronchial Ultrasound Radiofrequency of Lung Tumors in Ex-vivo Human Lungs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 20
- Locations
- 2
- Primary Endpoint
- To analyze the relationship of three spectral features of the radiofrequency of lung tumors in ex-vivo human lungs.
Study Overview
Brief Summary
This study will analyze spectral features of the radiofrequency of lung tumors in ex-vivo human lungs. The resected specimens will be evaluated using the spectrum analysis to determine the localization rate of the targets. Ultrasound measurement and images will be used for correlation of TS mode image findings with pathology by using HE and IHC slides of lung tumor and lymph node.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Any patients scheduled for lobectomy of anatomical segmental resection for malignant lung tumors.
- •18 years of age or older
Exclusion Criteria
- •Any patients with inability to give informed consent.
Arms & Interventions
Ex-Vivo
Intervention: Spectrum Analysis (Device)
Outcomes
Primary Outcomes
To analyze the relationship of three spectral features of the radiofrequency of lung tumors in ex-vivo human lungs.
Time Frame: Within an hour after resection.
From obtained ultrasound images, a linear regression line is quantified, and three ultrasonic spectral parameters including Midband-fit, Intercept, and Slope are calculated.
Secondary Outcomes
- To find the correlation of TS mode image findings with pathology by using lung tumor and lymph node samples.(Within an hour after resection)
- To clarify the feasibility of using the conventional EBUS scope to visualize solitary pulmonary nodules in an ex-vivo human lung.(Within an hour after resection)